Results 51 to 60 of about 57,211 (263)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Convergence Analysis of an Accelerated Iteration for Monotone Generalized α-Nonexpansive Mappings with a Partial Order

open access: yesJournal of Function Spaces, 2019
In this paper, we introduce a new accelerated iteration for finding a fixed point of monotone generalized α-nonexpansive mapping in an ordered Banach space.
Yi-An Chen, Dao-Jun Wen
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Elimination and fixed point iterations

open access: yesComputers & Mathematics with Applications, 1993
In fixed point iterations for linear systems, partial elimination effects a reduction of the spectral radii of Jacobi and Gauss-Seidel iteration matrices if the original Jacobi matrix is nonnegative. In the present paper the authors show that similar results also hold for nonlinear systems if the corresponding Jacobian matrix is nonnegative.
Milaszewicz, J.P., Abdel Masih, S.
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Common Fixed Point Approximation for Asymptotically Nonexpansive Mapping in Hyperbolic Space with Application

open access: yesAxioms
This study presents a common fixed-point iteration process that includes two asymptotically nonexpansive self-mappings in a hyperbolic space and their delta convergence. To support our results, we provide an example with a comparison table and sufficient
Tehreem Ishtiaq   +3 more
doaj   +1 more source

Convergence of modified S-iteration process for two asymptotically quasi-nonexpansive type mappings in CAT(0) spaces

open access: yesDemonstratio Mathematica, 2016
The purpose of this paper is to study convergence of a newly defined modified S-iteration process to a common fixed point of two asymptotically quasi-nonexpansive type mappings in the setting of CAT(0) space. We give a suffcient condition for convergence
Saluja G. S.
doaj   +1 more source

Fixed point iteration on pointsymmetric interference graphs [PDF]

open access: yesPerformance Evaluation, 1994
Interference graphs are used for performance analysis of multiprocessor interconnection networks. In order to model blocked transmissions, nodes can have three states: idle, active or blocked. The resulting steady state probability distribution has a non-product form.
van Damme, Rudolf M.J.   +1 more
openaire   +3 more sources

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