Results 71 to 80 of about 57,211 (263)

Hybrid Inertial Self-Adaptive Iterative Methods for Split Variational Inclusion Problems

open access: yesAxioms
Herein, we present two hybrid inertial self-adaptive iterative methods for determining the combined solution of the split variational inclusions and fixed-point problems.
Doaa Filali   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Three-Step Fixed Point Iteration for Generalized Multivalued Mapping in Banach Spaces

open access: yesJournal of Applied Mathematics, 2012
The convergence of three-step fixed point iterative processes for generalized multivalued nonexpansive mapping was considered in this paper. Under some different conditions, the sequences of three-step fixed point iterates strongly or weakly converge to ...
Zhanfei Zuo
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

On the fixed points of the iterated pseudopalindromic closure operator

open access: yesTheoretical Computer Science, 2011
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jamet, Damien   +3 more
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Strongly Convergence of Two Iterations For a Common Fixed Point with an Application

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2019
     In this paper, we study some cases of a common fixed point theorem for classes of firmly nonexpansive and generalized nonexpansive maps. In addition, we establish that the Picard-Mann iteration is faster than Noor iteration and we used Noor ...
Zahra Mahmood Mohamed Hasan   +1 more
doaj   +1 more source

On the Fixed Point Index of Iterates of Planar Homeomorphisms [PDF]

open access: yesProceedings of the American Mathematical Society, 1990
If f f is an orientation preserving homeomorphism of the plane with an isolated fixed point at the origin 0 and
openaire   +2 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

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