Results 111 to 120 of about 10,047 (211)

Optimal integration of photovoltaic sources and capacitor banks considering irradiance, temperature, and load changes in electric distribution system. [PDF]

open access: yesSci Rep
Fettah K   +9 more
europepmc   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

open access: yesBrain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland   +4 more
wiley   +1 more source

Targeting the noncatalytic activity of GSK3β modulates neuronal excitability in medium spiny neurons via Nav1.6 interactions

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Kinases phosphorylate ion channels, but their noncatalytic roles via protein–protein interactions (PPI) are less understood. Here, we identified the peptidomimetic ZL141 to characterize the PPI between GSK3β and Nav1.6, revealing a noncatalytic role for GSK3β in regulating Nav1.6 currents and neuronal excitability ...
Aditya K. Singh   +19 more
wiley   +1 more source

SOX30 Governs Synaptonemal Complex Assembly and Homologous Recombination in Male Meiosis

open access: yesCell Proliferation, EarlyView.
The transcription factor SOX30 directly binds promoter regions of SYCE1 and SYCE2 to mediate their transcriptional activation, thereby enabling proper assembly of central elements within the synaptonemal complex. Structural destabilisation of the synaptonemal complex in Sox30 KK spermatocytes triggers synaptic discontinuity, impairs homologous ...
Kangle Liu   +16 more
wiley   +1 more source

Technical Quality and Students' Perception of Endodontic Preclinical Training Using Natural or LikeReal Artificial Teeth

open access: yesEuropean Journal of Dental Education, EarlyView.
ABSTRACT Introduction This study evaluated and compared the technical quality of treatments performed during the preclinical training using artificial and natural teeth and the students' perceptions regarding their learning process with the 2 groups. Materials and Methods The study assessed the teeth used for preclinical training by 2nd‐year students ...
Gabriela Biagioni   +2 more
wiley   +1 more source

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