Results 131 to 140 of about 10,047 (211)

Anemia‐associated mutations disrupt the CDIN1‐Codanin1 complex in inherited congenital dyserythropoietic anemia I (CDA‐I) disease

open access: yesThe FEBS Journal, EarlyView.
Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal   +8 more
wiley   +1 more source

Design and analysis of a single source seven level common ground SC based multilevel inverter topology with high reliability. [PDF]

open access: yesSci Rep
Hussain MT   +8 more
europepmc   +1 more source

Lock, relax, load, and shoot: a molecular perspective on Nedd4 regulation

open access: yesThe FEBS Journal, EarlyView.
Structural basis of inactive and active states of the Nedd4 HECT E3 ligase subfamily, following a ‘lock, relax, load, and shoot’ mechanism. In the locked, autoinhibited state, intramolecular domain interactions restrain the HECT domain. Relaxation releases these restraints, allowing loading of ubiquitin onto the catalytic cysteine, followed by the ...
Masa Janosev   +2 more
wiley   +1 more source

Reputation and Asset Prices: Evidence From Trump Real Estate

open access: yesFinancial Management, EarlyView.
ABSTRACT We analyze the impact of brand reputation on asset prices by exploiting the prominence of Donald Trump in Manhattan real estate. Our quasi‐experiment identifies a 14.5% discount to condominiums in Trump‐branded buildings after controversies surrounding Trump's presidential candidacy began in June 2015 up to 2022.
Marlene Koch, Simon Stehle, Rémi Vivès
wiley   +1 more source

Uncertainty in Relation to Clinical Experience—A Qualitative Study on Dental Students' Reflections on Risk Assessment of Root Filled Teeth

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Aim In uncertain clinical situations, such as assessing the risk of exacerbation of apical periodontitis in root‐filled teeth, undergraduate students can benefit from being trained to reflect. This study aimed to explore how students specifically reflected on clinical experiences in relation to uncertainty when assessing a case involving a ...
Joséphine Brodén   +3 more
wiley   +1 more source

To Grandmother's House We Go: Informal Childcare and Female Labor Mobility

open access: yesInternational Economic Review, EarlyView.
ABSTRACT We document how childcare costs and the location of extended family influence the labor supply and mobility of US women. Women return to their home locations immediately before fertility events, suggesting that informal childcare needs may motivate home migration. Women who live near their parents have lower child earnings penalties.
Garrett Anstreicher, Joanna Venator
wiley   +1 more source

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