Results 41 to 50 of about 692,466 (358)
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
FINANCING OF FIXED ASSETS AS OBJECT OF STATISTICAL RESEARCH
Статистика и экономика, 2016 Statistical analysis of fixed assets as the most valuable component of national wealth is relevant not only to solve traditional problems associated with the assessment of the availability, structure and dynamics of economic assets.
Dmitry V. Dianov, Nikolay V. Gaifulin
doaj +1 more source
Rules of Fixed Assets Accounting Should Be Changed
Учёт. Анализ. Аудит, 2020 Nowadays the role of accounting in managing the economy of businesses is increasing. Accounting is one of the main information sources for making managerial decisions in organizations.
V. G. Get’man
doaj +1 more source
Comments on the Fixed Assets Investment Bill (draft) [PDF]
, 1994 Comments on a draft legislation regarding investment of fixed ...
Seidman, Ann, Seidman, Robert B.
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
THE ANALYSIS OF SOME INDICATORS OF FIXED ASSET REPRODUCTION MANAGMENT ASSESMENT
Вестник Кемеровского государственного университета, 2014 The paper analyses of certain indicators for assessment of fixed asset reproduction scale and intensity. An interpretation of the values taken by each of this indicators is given in order to identify standards of fixed assets reproduction.
A. S. Matievich
doaj
ENSURING FINANCIAL SECURITY IN RUSSIA’S NORTH AND ARCTIC REGIONS THROUGH FIXED ASSETS MANAGEMENT
Север и рынок: формирование экономического порядка, 2023 This study explores the management of fixed assets in the context of ensuring financial security for sustainable development in the North and Arctic regions of Russia.
Dmitriy S. Krapivin
doaj +1 more source
Resource consents - intangible fixed assets? Yes, but, too difficult by far! [PDF]
, 2000 Recent international attempts to draft an accounting standard (IAS38) which establishes the most widely acceptable treatment for intangible assets have sparked debate among standard setters, practising accountants and media analysts. Contentious issues
Hawkes, L. C., Tozer, L.
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Faktor-faktor Yang Mempengaruhi Optimalisasi Pemanfaatan Aset Tetap [PDF]
, 2016 This article examines determinants which influence the optimization of fixed assets utilization in Local Treasury and Asset Management Agency of Boven Digoel Regency. The number of population in this study was 77 respondents from government officials and
Kambu, A. (Arius) +2 more
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