Results 41 to 50 of about 687,321 (307)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Resource consents - intangible fixed assets? Yes, but, too difficult by far! [PDF]

open access: yes, 2000
Recent international attempts to draft an accounting standard (IAS38) which establishes the most widely acceptable treatment for intangible assets have sparked debate among standard setters, practising accountants and media analysts. Contentious issues
Hawkes, L. C., Tozer, L.
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

THE ANALYSIS OF SOME INDICATORS OF FIXED ASSET REPRODUCTION MANAGMENT ASSESMENT

open access: yesВестник Кемеровского государственного университета, 2014
The paper analyses of certain indicators for assessment of fixed asset reproduction scale and intensity. An interpretation of the values taken by each of this indicators is given in order to identify standards of fixed assets reproduction.
A. S. Matievich
doaj  

FINANCING OF FIXED ASSETS AS OBJECT OF STATISTICAL RESEARCH

open access: yesСтатистика и экономика, 2016
Statistical analysis of fixed assets as the most valuable component of national wealth is relevant not only to solve traditional problems associated with the assessment of the availability, structure and dynamics of economic assets.
Dmitry V. Dianov, Nikolay V. Gaifulin
doaj   +1 more source

Rules of Fixed Assets Accounting Should Be Changed

open access: yesУчёт. Анализ. Аудит, 2020
Nowadays the role of accounting in managing the economy of businesses is increasing. Accounting is one of the main information sources for making managerial decisions in organizations.
V. G. Get’man
doaj   +1 more source

Faktor-faktor Yang Mempengaruhi Optimalisasi Pemanfaatan Aset Tetap [PDF]

open access: yes, 2016
This article examines determinants which influence the optimization of fixed assets utilization in Local Treasury and Asset Management Agency of Boven Digoel Regency. The number of population in this study was 77 respondents from government officials and
Kambu, A. (Arius)   +2 more
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

ENSURING FINANCIAL SECURITY IN RUSSIA’S NORTH AND ARCTIC REGIONS THROUGH FIXED ASSETS MANAGEMENT

open access: yesСевер и рынок: формирование экономического порядка, 2023
This study explores the management of fixed assets in the context of ensuring financial security for sustainable development in the North and Arctic regions of Russia.
Dmitriy S. Krapivin
doaj   +1 more source

Ipteks Pengendalian Intern Aset Tetap pada PT. PLN (Persero) Up3 Manado [PDF]

open access: yes, 2018
In carrying out all its operational activities, a company needs and has never been separated from the role of fixed assets. Fixed assets are one of the assets of a company that has a useful life of more than one year and has a large materiality value. At
Gerung, I. R. (Ireyne)   +1 more
core  

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