Results 61 to 70 of about 1,690,614 (302)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Mediterranean Journal of Social Sciences, 2015 Making the economic decisions depend to a large extent on the quality and level of information that owns. The quality and the reliable information obtained from financial statements is very important for successful decision-making and the economic development of a country, for the development of financial markets, to promote the entry of foreign ...
Shqipe Xhaferri, Albana Demi
openaire +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Comparative Survey on the Records of Fixed Assets of Companies and Public Institutions [PDF]
This paper deals by way of comparison with the theoretical and practical methods to record the output and input of tangible fixed assets (non-current assets) in and from the patrimony of companies, on the one side and of public institutions, on the other
Ecobici, Nicolae
core
Accounting of fixed assets repair [PDF]
, 2021 MOSCALIUC, Nicoleta. Contabilitatea reparației mijloacelor fixe = Accounting of fixed assets repair. In: Provocările contabilităţii în viziunea tinerilor cercetători: Conf. şt. intern. studenţească, ISSC 2021: Culegere de articole ştiinţifice, Ed. a 5-a,
Moscaliuc, Nicoleta
core +1 more source
ROLE OF MAIN ACTIVITIES IN FORMATION OF THE CAPITAL OF AN ENTERPRISE, THEIR EVALUATION AND CONTROL
Фінансово-кредитна діяльність: проблеми теорії та практики, 2019 The article deals with the problem of valuation and control of non-current assets, in particular of fixed assets, determination of their role in the formation of the enterprise’s own capital, their correct and reliable evaluation at the enterprise.
O. H. Chyrva +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
New Capital Estimates for China [PDF]
Data on physical capital are an indispensable part of economic growth and efficiency studies. In the case of China, fixed asset time series are usually derived either by aggregating gross fixed capital formation data over time, net of depreciation, or by
Carsten A. Holz
core
REVALUASI ASET UNTUK TUJUAN PERPAJAKAN, AMBIL ATAU JANGAN
Profita, 2016 The Government has launched a policy of taxation through the Minister of Finance numbered 191/PMK.010/2015 on Revaluation of Fixed Assets Proposed in the Year 2015 and 2016.
YUSUF S. BASAR
doaj +1 more source