Results 81 to 90 of about 1,690,614 (302)
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
, 1994 In a time of crumbling infrastructure, rising replacement costs, and a dwindling supply of capital, it is necessary to maximize the benefits of investment in long-term tangible assets.
Peterson, Raymond H.
core
Topical Problems of Accounting of Fixed Assets
Учёт. Анализ. Аудит, 2019 The fixed assets are among the most frequent types of assets of any enterprise, regardless of its industry sector, form of ownership, management and organizational-legal forms. The emergence of Provisions in the accounting of some objects raises a number
LARISA K. Nikandrova, GALINA А. Skachko
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Aspects Regarding the Definition, Recognition and Valuation of Fixed Assets According to the Accounting Rules of the Republic of Moldova [PDF]
Revista de Studii FinanciareThe accounting legislative and regulatory framework of the Republic of Moldova treats fixed assets in a specific way, according to local accounting practices. In the framework of the scientific research carried out, the aim was to analyse the regulations
Anatolie Iachimovschi +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
SPECIFICATION OF ACCOUNTING OF FIXED ASSETS UNDER INTERNATIONAL AND RUSSIAN STANDARDS
Вестник университета, 2017 The problems of definition and recognition of fixed assets are considered. The current Accounting Regulation «Accounting for Fixed Assets» is compared with the International Standard «Fixed Assets» in terms of determining and recognizing objects in ...
T. Rogulenko, E. Egorova
doaj
IEEE Access, 2019 Fixed assets investment is a driving factor in facilitating urbanization and economic growth. The local governments have spent a lot of budgets on the construction of fixed assets.
Li Wang +5 more
doaj +1 more source