Results 41 to 50 of about 24,603 (266)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

ACCOUNTABILITY FOR GOVERNANCE OF GOVERNMENT FIXED ASSETS

Jurnal Akuntansi Multiparadigma, 2022
Abstrak - Akuntabilitas Tata Kelola Aset Tetap Pemerintah Tujuan Utama – Penelitian ini berupaya untuk menelaah permasalahan penyimpangan dalam pengelolaan aset tetap pada pemerintah daerah dan upaya penyelesaiannya.
Aristanti Widyaningsih
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Information Disclosure on Fixed Assets in Non-Financial Reporting in the Mechanical Engineering Industry

Учёт. Анализ. Аудит
The information about fixed assets is crucial for users to understand the operations of commercial organizations, as these assets play a vital role in their activities. The required information about fixed assets is incomplete in organizations’ financial
I. V. Alekseeva, E. Yu. Andryushchenko
doaj   +1 more source

Investments in fixed assets and depreciation of fixed assets: theoretical and practical aspects of study and analysis

Статистика и экономика, 2017
It is indicated that domestic economy is experiencing a shortage of investment.The acceleration of the processes of import substitution is one of the most important challenges facing the domestic economy at present.Investments, especially capital ...
Irina D. Demina, Elena I. Larionova, Tatiana I. Chinaeva   +2 more
doaj   +1 more source

FIXED ASSETS ACCOUNT

, 2023
Asosiy vositalarni hisobga olishdagi asosiy qoidalar asosiy vositalarning aktiv sifatida tan olish paytini aniqlash, ularning mazkur aktivlarga nisbatan qo‘llanilishi shart bo‘lgan balans qiymatini va amortizatsiya hisoblash usullarini belgilash, shuningdek asosiy vositalarning balans qiymatidagi boshqa o‘zgarishlarni va ularning chiqib ketishidan ...
Ilmuradova Shohsanam Nurbekqizi, Maxmudov Jasurbek Ergashovich   +1 more
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Fixed asset management [PDF]

Poslovna ekonomija, 2015
Decades of poor management of fixed assets have brought Serbia to the state of a complete technological inferiority in comparison to the developed world. One of the reasons for all the aforementioned is definitely the fact that information on fixed assets, as a rule, used to be overshadowed by the information on the financial status of an enterprise ...
Slobodan Vidakovic, Milan Ljubojevic, Izet Banda   +2 more
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source