Results 101 to 110 of about 1,967,755 (312)
BAYES' ESTIMATES OF THE DOUBLE HURDLE MODEL IN THE PRESENCE OF FIXED COSTS [PDF]
We present a model of market adoption (participation) where the presence of non-negligible fixed costs leads to non-zero censoring of the traditional double-hurdle regression.
Barrett, Christopher B. +2 more
core +1 more source
Strongly Polynomial Primal-Dual Algorithms for Concave Cost Combinatorial Optimization Problems [PDF]
, 2012 We introduce an algorithm design technique for a class of combinatorial optimization problems with concave costs. This technique yields a strongly polynomial primal-dual algorithm for a concave cost problem whenever such an algorithm exists for the fixed-
Magnanti, Thomas L., Stratila, Dan
core +2 more sources
Fixed costs and long-lived investments [PDF]
Journal of Monetary Economics, 2014 Abstract Fixed costs models are difficult to analyze because they feature non-degenerate, time-varying distributions of capital across firms. If investments are sufficiently long-lived however then the cross-sectional distribution of capital holdings has virtually no bearing on the equilibrium and the aggregate behavior of fixed-cost models is ...
openaire +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Bertrand's price competition in markets with fixed costs [PDF]
This paper provides necessary and sufficient conditions for the existence of a pure strategy Bertrand equilibrium in a model of price competition with fixed costs.
Alejandro Saporiti, German Coloma
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Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
SHS Web of Conferences, 2017 The paper considers impact of entry barriers on the social welfare. Despite the common opinion that entry barriers are always bad, the excessive number of firms means, all pros aside, duplicated fixed costs. It is shown that the socially effective number
Filatov Alexander, Makolskaya Yana
doaj +1 more source
Understanding International Portfolio Diversification and Turnover Rates [PDF]
This paper argues that fixed trading costs in international asset markets help explain equity home bias. This contrasts with explanations prevalent in international macroeconomics, which tend to be based on trading frictions instead in international ...
Amir Amadi, Paul Bergin
core
Seasonality and Costs of Production on Irish dairy farms from 1994-2008 [PDF]
, 2010 working paperPrevious research has highlighted the economic advantages of spring calving in countries such as Ireland that have a long spring/summer grazing season. However, the widespread adoption of such a production system leads to a highly seasonal
Harte, Laurence +2 more
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