Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Does state-level supplemental nutrition assistance program access reduce firearm mortality among black youth? A two-way fixed effects analysis of age-stratified and cause-specific outcomes across 22 states, 2000-2020. [PDF]
Johnson ED +5 more
europepmc +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Hospitalization- and death-related financial and employment effects in parents of children with life-limiting conditions: a fixed-effects analysis. [PDF]
Mitterer S +5 more
europepmc +1 more source
Approaches for Modeling Vertical Distribution of Maximum Knot Size in Black Spruce: A Comparison of Fixed- and Mixed-Effects Nonlinear Models [PDF]
John A. Kershaw +2 more
openalex +1 more source
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
The association between cesarean birth and breastfeeding initiation in Odisha, India: A mother fixed effects analysis. [PDF]
Smita, Franz N, Coffey D.
europepmc +1 more source
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Dissecting the digital divide: A household fixed effects approach to estimating gender gaps in digital skills of youth in low- and middle-income economies. [PDF]
Avanesian G +3 more
europepmc +1 more source

