Results 61 to 70 of about 560,761 (277)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Fixed Points by a New Iteration Method [PDF]

open access: yesProceedings of the American Mathematical Society, 1974
The following result is shown. If T T is a lipschitzian pseudo-contractive map of a compact convex subset E E of a Hilbert space into itself and x 1 {x_1} is any point in E E , then a certain mean value sequence defined by
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Convergence Analysis of an Accelerated Iteration for Monotone Generalized α-Nonexpansive Mappings with a Partial Order

open access: yesJournal of Function Spaces, 2019
In this paper, we introduce a new accelerated iteration for finding a fixed point of monotone generalized α-nonexpansive mapping in an ordered Banach space.
Yi-An Chen, Dao-Jun Wen
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

On the two-point boundary value problems using variational-fixed point iterative scheme [PDF]

open access: yes, 2017
We developed a new scheme which is obtained by linking finite element, fixed point iterations and variational iteration technique known as variational-fixed point iterative scheme for attacking higher order differential equations.
Kilicman, Adem, Wadai, Mutah
core  

Errata to “Elimination and fixed point iterations”

open access: yesComputers & Mathematics with Applications, 1994
A programming mistake led to numerical errors in Tables 4.1 and 4.2 of the authors' paper [ibid. 25, No. 5, 43-53 (1993; Zbl 0780.65030)]. The two leftmost columns corresponding to the Newton iterations and their residuals in both tables are correct; on the other hand, those corresponding to the Newton-Fourier iterations are wrong.
Milaszewicz, J. P., Masih, S. Abdel
openaire   +1 more source

Fixed point iteration for pseudocontractive maps [PDF]

open access: yesProceedings of the American Mathematical Society, 1999
Let K K be a compact convex subset of a real Hilbert space, H H ; T : K → K T:K\rightarrow K a continuous pseudocontractive map. Let { a n } , { b ...
Chidume, C. E., Moore, Chika
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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