Results 101 to 110 of about 6,000,123 (363)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Approximately Quintic and Sextic Mappings Form -Divisible Groups into Ŝerstnev Probabilistic Banach Spaces: Fixed Point Method

, 2011
Using the fixed point method, we investigate the stability of the systems of quadratic-cubic and additive-quadratic-cubic functional equations with constant coefficients form r-divisible groups into Ŝerstnev probabilistic Banach spaces.
M. E. Gordji, Y. Cho, M. Ghaemi, H. Majani   +3 more
semanticscholar   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

An Extragradient Method for Mixed Equilibrium Problems and Fixed Point Problems

Fixed Point Theory and Applications, 2009
The purpose of this paper is to investigate the problem of approximating a common element of the set of fixed points of a demicontractive mapping and the set of solutions of a mixed equilibrium problem.
Liou Yeong-Cheng, Wu Yuh-Jenn, Yao Yonghong   +2 more
doaj  

THE FIXED POINT ITERATIONS METHOD FOR THE CONTRACTION MAPPING

MM Science Journal
This paper studies the fixed point iterations method that considers the contraction mapping and one of its applications for the parameter re-estimation of the normal (Gaussian) distribution, where the presence of outliers is considered. In order to study the observed method Banach’s fixed point theorem is presented, where it is shown that the ...
V. Novoselac, A. Katic, Z. Matijasevic, M. Culetic Condric   +3 more
openaire   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Viscosity Approximation Methods for Fixed-Points Problems

Journal of Mathematical Analysis and Applications, 2000
The aim of this work is to propose viscosity approximation methods which amounts to selecting a particular fixed-point of a given nonexpansive self-mapping.
openaire   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

An extragradient-like approximation method for variational inequalities and fixed point problems

Fixed Point Theory and Applications, 2011
The purpose of this paper is to investigate the problem of finding a common element of the set of fixed points of an asymptotically strict pseudocontractive mapping in the intermediate sense and the set of solutions of a variational inequality problem ...
Wong Ngai-Ching, Yao Jen-Chih, Ansari Qamrul, Ceng Lu-Chuan   +3 more
doaj