Results 111 to 120 of about 1,874,752 (330)

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

A new proof of the Stable Manifold Theorem for hyperbolic fixed points on surfaces [PDF]

open access: yesarXiv, 2003
We introduce a new technique for proving the classical Stable Manifold theorem for hyperbolic fixed points. This method is much more geometrical than the standard approaches which rely on abstract fixed point theorems. It is based on the convergence of a canonical sequence of ``finite time local stable manifolds'' which are related to the dynamics of a
arxiv  

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

Fixed points and semifree bordism [PDF]

open access: yesarXiv, 2019
We apply fixed-point techniques to compute the coefficient ring of semifree geometric circle-equivariant complex cobordism with isolated fixed points, recovering a 2004 result of Sinha through 19th-century methods.
arxiv  

Core many-to-one matchings by fixed-point methods [PDF]

open access: green, 2003
Federico Echenique, Jorge Oviedo
openalex   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Properties of Fixed Points of Generalised Extra Gradient Methods Applied to Min-Max Problems [PDF]

open access: yesarXiv
This paper studies properties of fixed points of generalised Extra-gradient (GEG) algorithms applied to min-max problems. We discuss connections between saddle points of the objective function of the min-max problem and GEG fixed points. We show that, under appropriate step-size selections, the set of saddle points (Nash equilibria) is a subset of ...
arxiv  

Fixed point sets in digital topology, 1 [PDF]

open access: yesarXiv, 2019
In this paper, we examine some properties of the fixed point set of a digitally continuous function. The digital setting requires new methods that are not analogous to those of classical topological fixed point theory, and we obtain results that often differ greatly from standard results in classical topology. We introduce several measures related to
arxiv  

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