Results 111 to 120 of about 6,000,123 (363)
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Iterative Methods for Finding Solutions of a Class of Split Feasibility Problems over Fixed Point Sets in Hilbert Spaces [PDF]
, 2019 Suthep Suantai +2 more
openalex +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Shrinking projection method for proximal split feasibility and fixed point problems
Results in Nonlinear Analysis, 2019 In this paper, we consider and study proximal split feasibility and fixed point problem. For solving the problems, we introduce an iterative algorithm with shrinking projection technique. It is proven that the sequence generated by the proposed iterative
Jinzuo Chen
doaj
Strong convergence with a modified iterative projection method for\n hierarchical fixed point problems and variational inequalities [PDF]
, 2014 İbrahim Karahan, Murat Özdemir
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Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Analytic and empirical study of the rate of convergence of some iterative methods
Journal of Numerical Analysis and Approximation Theory, 2015 We study analytically and empirically the rate of convergence of two \(k\)-step fixed point iterative methods in the family of methods \[ x_{n+1}=T(x_{i_0+n-k+1},x_{i_1+n-k+1},\dots, x_{{i_{k-1}+n-k+1}}),\,n\geq k-1, \] where \(T\colon X^k\rightarrow ...
Vasile Berinde +2 more
doaj +2 more sources
ITERATIVE METHODS FOR APPROXIMATION OF FIXED POINTS AND THEIR APPLICATIONS
Journal of the Operations Research Society of Japan, 2000 Summary: We deal with iterative methods for approximation of fixed points and their applications. We first discuss fixed point theorems for a nonexpansive mapping or a family of nonexpansive mappings. In particular, we state a fixed point theorem which answered affirmatively a problem posed during the Conference on Fixed Point Theory and Applications ...
openaire +2 more sources
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source