Results 121 to 130 of about 1,874,752 (330)

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

Fixed-point Iterative Sweeping Methods for Static Hamilton-Jacobi Equations [PDF]

, 2006
Shanqin Chen, Yong‐Tao Zhang, Hongkai Zhao   +2 more
openalex   +1 more source

Newton-like methods for the computation of fixed points

Computers & Mathematics with Applications, 1984
AbstractThe celebrated Banach fixed point theorem provides conditions which assure that the method of successive substitution is convergent; the convergence, however, may take place very slowly so that it may be desirable to use a Newton-like method for the computation of the fixed point.
openaire   +2 more sources

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

Molecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang, Simone van de Weerd, Veerle Lammers, Sander van Hooff, Inge van den Berg, Saskia van den Bergh, Miriam Koopman, Jan N. IJzermans, Jeanine M. L. Roodhart, Jan Koster, Jan Paul Medema   +10 more
wiley   +1 more source

Fixed Points and Cycles of the Kaprekar Transformation: 2. Even bases [PDF]

arXiv
We develop a classification of the fixed points and cycles of the Kaprekar transformation in even bases. The most numerous fixed points and cycles are those we denote symmetric and almost-symmetric; the structure of the cycles of these classes in base $b$ is determined by subgroups and cosets in the multiplicative group modulo $b-1$. We provide methods
arxiv  

Fixed Point Methods for the Generalized Stability of Functional Equations in a Single Variable [PDF]

, 2007
Liviu Cădariu, Viorel Radu
openalex   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

On coupled non-linear Schrödinger systems with singular source term

AIMS Mathematics
This work studies a coupled non-linear Schrödinger system with a singular source term. First, we investigate the question of the local existence of solutions.
Saleh Almuthaybiri, Tarek Saanouni
doaj   +1 more source

Properties of a fixed point method.

, 1999
A general pseudo-Bayes Fixed Point method for making inference about parameters of statistical models is recalled. The Fixed Point estimates are actually pseudo-Bayes in that they depend on a prior parametric class of densities rather than a particular choice for prior. Different from maximum likelihood, they take into account the full structure of the
openaire   +1 more source