Results 131 to 140 of about 1,874,752 (330)

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

On the nonlinear Schrödinger equation with critical source term: global well-posedness, scattering and finite time blowup

open access: yesAIMS Mathematics
This study explored the time asymptotic behavior of the Schrödinger equation with an inhomogeneous energy-critical nonlinearity. The approach follows the concentration-compactness method due to Kenig and Merle.
Saleh Almuthaybiri   +2 more
doaj   +1 more source

The secant method and fixed points of nonlinear operators

open access: yesMonatshefte f�r Mathematik, 1988
Our results answer the following question: given that a mapping has a fixed point, when is it true that the Secant iterates produce a sequence of nearby points which converge to the fixed point? We assume only that the nonlinear operator has a Holder continuous Frechet-derivative at the fixed point.
openaire   +2 more sources

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Optimal investment game for two regulated players with regime switching

open access: yesAIMS Mathematics
This paper investigated a zero-sum stochastic investment game for two investors in a regime-switching market with common random time solvency regulations.
Lin Xu   +3 more
doaj   +1 more source

Fixed Point Diffusion Models [PDF]

open access: yesarXiv
We introduce the Fixed Point Diffusion Model (FPDM), a novel approach to image generation that integrates the concept of fixed point solving into the framework of diffusion-based generative modeling. Our approach embeds an implicit fixed point solving layer into the denoising network of a diffusion model, transforming the diffusion process into a ...
arxiv  

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