Results 161 to 170 of about 5,767,953 (360)
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka+10 more
wiley +1 more source
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu+15 more
wiley +1 more source
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
A general iterative method for equilibrium problems and fixed point problems in Hilbert spaces
Somyot Plubtieng, Rattanaporn Punpaeng
openalex +1 more source
Strong convergence of a hybrid method for monotone variational inequalities and fixed point problems [PDF]
Yonghong Yao+3 more
openalex +1 more source
A Fixed-Point Method for Weighting Terms in Verbose Informational Queries
Jiaul H. Paik, Douglas W. Oard
semanticscholar +1 more source
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair+17 more
wiley +1 more source
A relaxed hybrid steepest descent method for common solutions of generalized mixed equilibrium problems and fixed point problems [PDF]
Nawitcha Onjai-uea+2 more
openalex +1 more source
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes+20 more
wiley +1 more source
Strong convergence theorems by hybrid projection methods for equilibrium problems and fixed point problems of the asymptotically quasi-ϕ-nonexpansive mappings [PDF]
Jong Kyu Kim
openalex +1 more source