Results 61 to 70 of about 10,928,537 (263)

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Some fixed point theorems for discontinuous mappings [PDF]

open access: yes
This paper provides a fixed point theorem à la Schauder, where the mappings considered are possibly discontinuous. Our main result generalizes and unifies several well-known results.Schauder fixed point theorem, Brouwer fixed point theorem, discontinuity.
Philippe Bich
core  

Existence Of A Unique Mild Solution To A Fractional Thermostat Model Via A Rus'S Fixed Point Theorem

open access: yes
The purpose of this paper is to study the existence of a unique solution of a nonlinear fractional boundary value problem which can be considered as the fractional version of the thermostat model.
Lopez, B., Sadarangani, K., Harjani, J.
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Double solutions of three-point boundary-value problems for second-order differential equations

open access: yesElectronic Journal of Differential Equations, 2004
A double fixed point theorem is applied to yield the existence of at least two nonnegative solutions for the three-point boundary-value problem for a second-order differential equation, $$displaylines{ y'' + f(y)=0,quad 0 leq t leq 1,cr y(0) =0,quad y(p)
Johnny Henderson
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Existence of solutions for second-order differential equations and systems on infinite intervals

open access: yesElectronic Journal of Differential Equations, 2009
We study the existence of nontrivial solutions to the boundary-value problem $$displaylines{ -u''+cu'+lambda u = f(x,u),quad -infty <x<+infty , cr u(-infty )=u(+infty ) =0 }$$ and to the system $$displaylines{ -u''+c_1u'+lambda _1u = f(x,u ...
Toufik Moussaoui, Radu Precup
doaj  

Strong Convergence Theorems for the Generalized Split Common Fixed Point Problem

open access: yesJournal of Applied Mathematics, 2012
We introduce the generalized split common fixed point problem (GSCFPP) and show that the GSCFPP for nonexpansive operators is equivalent to the common fixed point problem.
Cuijie Zhang
doaj   +1 more source

Nonlinear Inequality, Fixed Point and NashEquilibrium [PDF]

open access: yes
In this paper, we give new sufficient conditions for the existence of a solution of theg-maximum equality. As a consequence, we prove a new fixed point theorem.
Moussa Larbani   +2 more
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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