Results 81 to 90 of about 411,606 (266)

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Well-Posedness of the Fixed Point Problem of Multifunctions of Metric Spaces

Mathematics
We consider a class of metrics which are equivalent to the Hausdorff metric in some sense to establish the well-posedness of fixed point problems associated with multifunctions of metric spaces, satisfying various generalized contraction conditions ...
Nozara Sundus, Basit Ali, Maggie Aphane
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

On Fixed Point and Almost Fixed Point Problems of Lower Semicontinuous Type Multivalued Mappings

Acta Mathematica Sinica, English Series, 2005
The authors obtain almost fixed point theorems and fixed point theorems for lower semicontinuous type multivalued mappings in metrizable H-spaces. As an application, they obtain a nonempty intersection theorem for a multivalued mapping on a compact H-convex space. The main results are good variants and generalizations of the almost fixed point theorems
Wu, Xian, Luan, Liangyu
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Strong Convergence of the Viscosity Approximation Process for the Split Common Fixed-Point Problem of Quasi-Nonexpansive Mappings

Journal of Applied Mathematics, 2012
Very recently, Moudafi (2011) introduced an algorithm with weak convergence for the split common fixed-point problem. In this paper, we will continue to consider the split common fixed-point problem.
Jing Zhao, Songnian He
doaj   +1 more source

Inertial Method for Bilevel Variational Inequality Problems with Fixed Point and Minimizer Point Constraints

Mathematics, 2019
In this paper, we introduce an iterative scheme with inertial effect using Mann iterative scheme and gradient-projection for solving the bilevel variational inequality problem over the intersection of the set of common fixed points of a finite number of ...
Seifu Endris Yimer, Poom Kumam, Anteneh Getachew Gebrie, Rabian Wangkeeree   +3 more
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

On positive solutions for some second-order three-point boundary value problems with convection term

Journal of Inequalities and Applications, 2019
In this paper, a fixed point theorem in a cone and some inequalities of the associated Green’s function are applied to obtain the existence of positive solutions of second-order three-point boundary value problem with dependence on the first-order ...
Yongfang Wei, Zhanbing Bai, Sujing Sun
doaj   +1 more source