Results 111 to 120 of about 1,116,885 (306)
On Fixed Points for Semi-Groups of Linear Operators [PDF]
Bertram Yood
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Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin+2 more
wiley +1 more source
On the envelope of the axes of a system of conics passing through three fixed points [PDF]
R. E. Allardice
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Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi+5 more
wiley +1 more source
67. Circles are drawn through two fixed points. Trace the path of a point which cuts them all at the same angle. (Question 172, p.89.) [PDF]
A. Lodge, F. S. Macaulay
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Barrett O'Neill, Ernst Straus
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Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz+5 more
wiley +1 more source
Extremal fixed points and Diophantine equations
The coupling constants of fixed points in the ϵ expansion at one loop are known to satisfy a quadratic bound due to Rychkov and Stergiou. We refer to fixed points that saturate this bound as extremal fixed points.
Christopher P. Herzog+3 more
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Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer+7 more
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