Results 131 to 140 of about 4,586,045 (294)
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
A Closed-cycle Refrigerator for Realizing Low-Temperature Fixed Points
, 2004 In order to accommodate the MULTICELLS Project output devices, a cryogen-free refrigerator has been designed and built at the Istituto di Metrologia “G.Colonnetti” (IMGC). The cryostat is a Gifford-McMahon refrigerator with two cooling stages. With the
MAZZOLENI F +8 more
core
Asymptotic stability results for certain integral equations
Electronic Journal of Differential Equations, 2005 This paper shows the existence of asymptotically stable solutions to an integral equation. This is done by using a fixed point theorem, and without requiring that the solutions be bounded.
Cezar Avramescu, Cristian Vladimirescu
doaj
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Fixed points for planar maps with multiple twists, with application to nonlinear equations with indefinite weight. [PDF]
Philos Trans A Math Phys Eng Sci, 2021 Margheri A, Rebelo C, Zanolin F.
europepmc +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Guide to the Realization of the ITS-90 - Metal Fixed Points for Contact Thermometry [PDF]
, 2016 This paper is a part of guidelines, prepared on behalf of the Consultative Committee for Thermometry, on the methods for realizing the International Temperature Scale of 1990 (ITS-90).
Tamba, J. +6 more
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Asymptotic fixed points for nonlinear contractions
Fixed Point Theory and Applications, 2005 Recently, W. A. Kirk proved an asymptotic fixed point theorem for nonlinear contractions by using ultrafilter methods. In this paper, we prove his theorem under weaker assumptions. Furthermore, our proof does not use ultrafilter methods.
Chen Yong-Zhuo
doaj