Results 141 to 150 of about 4,734,689 (297)

Asymptotic fixed points for nonlinear contractions

open access: yesFixed Point Theory and Applications, 2005
Recently, W. A. Kirk proved an asymptotic fixed point theorem for nonlinear contractions by using ultrafilter methods. In this paper, we prove his theorem under weaker assumptions. Furthermore, our proof does not use ultrafilter methods.
Chen Yong-Zhuo
doaj  

Nonlinear Inequality, Fixed Point and NashEquilibrium [PDF]

open access: yes
In this paper, we give new sufficient conditions for the existence of a solution of theg-maximum equality. As a consequence, we prove a new fixed point theorem.
Moussa Larbani   +2 more
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Fixed Points in Linear Regression [PDF]

open access: yes
There is a set of points in the plane whose elements correspond to the observations that are used to generate a simple least-squares regression line. Each value of the independent variable in the observations matches up with one of these points, which ...
Farnsworth, David L
core  

Fixed points and stationary points of dissipative multivalued maps

open access: yes, 1980
Fixed or stationary points of multivalued maps are seen to exist in the presence of various entropy functions for the map. Generalizations of the Banach-Picard and Caristi fixed point theorems are presented.
Jean-Pierre Aubin, Jerrold Siegel
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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