Results 81 to 90 of about 1,116,885 (306)

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Fixed points of multivalued nonexpansive maps

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1991
Fixed point theorems for multivalued contractive-type and nonexpansive-type maps on complete metric spaces and on certain closed bounded convex subsets of Banach spaces have been proved. They extend some known results due to Browder, Husain and Tarafdar,
T. Husain, Abdul Latif
doaj   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Fixed Points and Generalized Hyers-Ulam Stability

open access: yesAbstract and Applied Analysis, 2012
In this paper we prove a fixed-point theorem for a class of operators with suitable properties, in very general conditions. Also, we show that some recent fixed-points results in Brzdęk et al., (2011) and Brzdęk and Ciepliński (2011) can be obtained ...
L. Cădariu, L. Găvruţa, P. Găvruţa
doaj   +1 more source

Fixed points and braids

open access: yesInventiones Mathematicae, 1984
For a self-map f of a compact connected polyhedron X the Nielsen number N(f) of f is defined to be the number of essential fixed point classes of f. N(f) is a lower bound for the number of fixed points of every map homotopic to f. This lower bound is known to be realizable if X has no local separating points and X is not a surface (closed or with ...
openaire   +2 more sources

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Generating Geometric Patterns Using Complex Polynomials and Iterative Schemes

open access: yesAxioms
Iterative procedures have been proved as a milestone in the generation of fractals. This paper presents a novel approach for generating and visualizing fractals, specifically Mandelbrot and Julia sets, by utilizing complex polynomials of the form QC(p ...
Asifa Tassaddiq   +4 more
doaj   +1 more source

Common fixed points of set-valued mappings

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2001
The main purpose of this paper is to obtain a common fixed point for a pair of set-valued mappings of Greguš type condition. Our theorem extend Diviccaro et al. (1987), Guay et al. (1982), and Negoescu (1989).
M. R. Singh, L. S. Singh, P. P. Murthy
doaj   +1 more source

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