Results 151 to 160 of about 7,647,352 (298)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
The 1994 Fermilab Fixed Target Program [PDF]
, 1994 This paper highlights the results of the Fermilab Fixed Target Program that were announced between October, 1993 and October, 1994. These results are drawn from 18 experiments that took data in the 1985, 1987 and 1990/91 fixed target running periods. For
Conrad, J.
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Results on structure functions from fixed-target experiments
, 1993 A review of proton and neutron structure function measurements fro fixed-target experiments is presented. Results on unpolarized structure functions have stabilized for {chi} > 0.1, and new results on lower {chi} measurements are appearing.
Hughes, E.
core
Charm and beauty measurements at Fermilab fixed target [PDF]
, 1993 Eighteen months after a successful run of the Fermilab fixed target program, interesting results from several experiments are available. This is the first time that more than one Fermilab fixed target experiment has reported the observation of beauty ...
Mishra, C. S.
core
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Illustrations of the need for fixed target experiments
, 1995 We give a number of reasons for performing fixed target scattering experiments, among which the test of universality of total cross sections at extremely high energies, the problem of the odderon, the tests of the Bourrely-Soffer-Wu model for total ...
Martin, André
core
AFTER@LHC: A Fixed-Target ExpeRiment at the LHC [PDF]
Proceedings of XXI International Workshop on Deep-Inelastic Scattering and Related Subjects — PoS(DIS 2013), 2013 Andry Rakotozafindrabe +15 more
openaire +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source