Results 21 to 30 of about 338,159 (191)
Quantitative assessment of antibody internalization with novel monoclonal antibodies against Alexa fluorophores. [PDF]
Antibodies against cell surface antigens may be internalized through their specific interactions with these proteins and in some cases may induce or perturb antigen internalization.
Sindy Liao-Chan +8 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
La presente investigación constituye la parte II de una línea tendiente a definir si hay absorción por mucosa bucal del flúor utilizado en enjuagues para prevenir la caries dental, lo cual expliaría la sobredosis de éste, detectada en orina 4 horas ...
Fanny Lucía Yepes Delgado +2 more
doaj
CONCENTRAÇÃO DE FLÚOR EM DIFERENTES ESPÉCIES DE PASTAGENS DA REGIÃO CARBOELÉTRICA DE CANDIOTA, RS. [PDF]
Estudos anteriores demonstraram uma considerável contaminação de pastagens da região carboelétrica de Candiota, RS. Neste trabalho 21 espécies de pastagens nativas desta região foram identificadas e analisadas quanto a seus teores de flúor.
Érico M. M. Flores +3 more
doaj
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
AbstrakPenyebab tersering fluor albus (keputihan) patologis adalah infeksi. Proses infeksi dapat dipicu oleh banyak hal, salah satunya adalah karena pemakaian panty liner.
Anisa Persia +2 more
doaj
Entendimento dos médicos pediatras na recomendação de cremes dentais na primeira infância
Para caracterizar o entendimento do pediatra na recomendação de cremes dentais na primeira infância – usualmente tida como o período que vai do nascimento até o início da idade escolar, aos seis anos – é preciso um olhar mais amplo, que contemple não só ...
Danilo Blank
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Objetivo: Determinar la frecuencia de cepillado y uso de pasta dental con flúor en niños de 4 a 6 años de edad, de la parroquia Ricaurte del cantón Cuenca.
Karelys Quezada Capelo +3 more
doaj +1 more source

