Results 21 to 30 of about 328,735 (192)

Heterocontrole da Fluoretação da Água de Abastecimento Público do Município de Cachoeira do Sul – RS

Revista da Faculdade de Odontologia de Porto Alegre, 2006
A fluoretação da água de abastecimento público tem sido considerada como um método econômico e de grande abrangência populacional para o controle da doença cárie.
Fabiane PIVA, Maximiano Ferreira TOVO, Paulo Floriani KRAMER   +2 more
doaj   +1 more source

Quantitative assessment of antibody internalization with novel monoclonal antibodies against Alexa fluorophores. [PDF]

PLoS ONE, 2015
Antibodies against cell surface antigens may be internalized through their specific interactions with these proteins and in some cases may induce or perturb antigen internalization.
Sindy Liao-Chan, Barbara Daine-Matsuoka, Nathan Heald, Tiffany Wong, Tracey Lin, Allen G Cai, Michelle Lai, Joseph A D'Alessio, Jan-Willem Theunissen   +8 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

"SOBREDOSIS DE FLÚOR, DETECTADA EN LA ORINA DE ADULTOS DESPUÉS DE ENJUAGUES CON SOLUCIÓN DE FLUORURO DE SODIO Y EN ADULTOS CUYA SOLUCIÓN DE FLÚOR DEL ENJUAGUE FUE INMEDIATAMENTE ENJUAGADA CON AGUA". PARTE II

Revista Facultad de Odontología Universidad de Antioquia, 1993
La presente investigación constituye la parte II de una línea tendiente a definir si hay absorción por mucosa bucal del flúor utilizado en enjuagues para prevenir la caries dental, lo cual expliaría la sobredosis de éste, detectada en orina 4 horas ...
Fanny Lucía Yepes Delgado , Raul Mejía Villa , María Ines Arbelaez Marin   +2 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Hubungan Pemakaian Panty Liner dengan Kejadian Fluor Albus pada Siswi SMA di Kota Padang Berdasarkan Wawancara Terpimpin (Kuisioner)

Jurnal Kesehatan Andalas, 2015
AbstrakPenyebab tersering fluor albus (keputihan) patologis adalah infeksi. Proses infeksi dapat dipicu oleh banyak hal, salah satunya adalah karena pemakaian panty liner.
Anisa Persia, Rina Gustia, Elizabeth Bahar   +2 more
doaj  

CONCENTRAÇÃO DE FLÚOR EM DIFERENTES ESPÉCIES DE PASTAGENS DA REGIÃO CARBOELÉTRICA DE CANDIOTA, RS. [PDF]

Ciência Florestal, 1992
Estudos anteriores demonstraram uma considerável contaminação de pastagens da região carboelétrica de Candiota, RS. Neste trabalho 21 espécies de pastagens nativas desta região foram identificadas e analisadas quanto a seus teores de flúor.
Érico M. M. Flores, Adelino Alvarez Filho, Elemar Schwingel, Ayrton F. Martins   +3 more
doaj  

Entendimento dos médicos pediatras na recomendação de cremes dentais na primeira infância

Revista da Faculdade de Odontologia de Porto Alegre, 2012
Para caracterizar o entendimento do pediatra na recomendação de cremes dentais na primeira infância – usualmente tida como o período que vai do nascimento até o início da idade escolar, aos seis anos – é preciso um olhar mais amplo, que contemple não só ...
Danilo Blank
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source