Results 31 to 40 of about 328,735 (192)

Factors associated with dental fluorosis in children and teenagers from the city of Montería, Colombia

Revista Facultad de Odontología Universidad de Antioquia, 2019
Introduction: dental fluorosis is the hypomineralization of enamel produced as a result of fluoride intake for a prolonged period during enamel formation.
Enalbis Esther Espitia-Cabralez, Milena Cecilia Lozano-Flórez, Martha Elena Montoya-Vega   +2 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

SOBREDOSIS DEL FLÚOR DETECTADA EN ORINA DE NIÑOS EN EDAD ESCOLAR DESPUÉS DE ENJUAGUES CON SOLUCIÓN DE FLUORURO DE SODIO, UTILIZADO EN PREVENCIÓN DE CARIES DENTAL PARTE I

Revista Facultad de Odontología Universidad de Antioquia, 1992
Con el propósito de determinar presencia de flúor sistémico después de la aplicación de los enjuagues con fluoruro de sodio al 2% en niños en edad escolar, se hizo análisis de flúor en la orina de dos grupos de niño: experimental y control.
Fanny Lucía Yepes Delgado , Raul Mejía Villa, María Ines Arbelaez Marin   +2 more
doaj  

Frecuencia de cepillado y uso de pasta dental con flúor en niños de 4 a 6 años de edad en la parroquia Ricaurte del cantón Cuenca

Revista Científica Especialidades Odontológicas UG
Objetivo: Determinar la frecuencia de cepillado y uso de pasta dental con flúor en niños de 4 a 6 años de edad, de la parroquia Ricaurte del cantón Cuenca.
Karelys Quezada Capelo, María Elizabeth Moscoso Abad, Sandra Saquisili Suquitana, Verónica Verdugo Tinitana   +3 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Níveis de substituição do fosfato bicálcico pelo monobicálcico em dietas para suínos nas fases de crescimento e terminação Levels of substitution of phosphate dicalcium by monodicalcium in the diets of swine in the growing and finishing phases

Revista Brasileira de Zootecnia, 2005
Cinqüenta e seis leitões (peso médio inicial de 28,47 kg) foram distribuídos em um delineamento experimental de blocos casualizados, em esquema fatorial 4 x 2 (níveis de substituição do fosfato bicálcico x sexo), com quatro repetições para machos e três ...
Alexandre de Oliveira Teixeira, Darci Clementino Lopes, Paulo Cezar Gomes, João Batista Lopes, Leidimara Feregueti Costa, Vanusa Patrícia de Araújo Ferreira, Sérgio de Miranda Pena, José Aparecido Moreira, Silvano Büsen   +8 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Salivary Fluoride level in preschool children after toothbrushing with standard and low fluoride content dentifrice, using the transversal dentifrice application technique: pilot study [PDF]

RGO: Revista Gaúcha de Odontologia, 2008
Objective: To investigate the salivary fluoride concentration in pre-school children after toothbrushing with dentifrice containing standard (1100ppmF/NaF) and low (500ppmF/NaF) fluoride concentration, using the transversal technique of placing the ...
Fabiana Jandre Melo
doaj  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source