Results 31 to 40 of about 428,478 (285)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Níveis de substituição do fosfato bicálcico pelo monobicálcico em dietas para suínos nas fases de crescimento e terminação Levels of substitution of phosphate dicalcium by monodicalcium in the diets of swine in the growing and finishing phases

Revista Brasileira de Zootecnia, 2005
Cinqüenta e seis leitões (peso médio inicial de 28,47 kg) foram distribuídos em um delineamento experimental de blocos casualizados, em esquema fatorial 4 x 2 (níveis de substituição do fosfato bicálcico x sexo), com quatro repetições para machos e três ...
Alexandre de Oliveira Teixeira, Darci Clementino Lopes, Paulo Cezar Gomes, João Batista Lopes, Leidimara Feregueti Costa, Vanusa Patrícia de Araújo Ferreira, Sérgio de Miranda Pena, José Aparecido Moreira, Silvano Büsen   +8 more
doaj   +1 more source

Prescrição médica de flúor na saúde infantil [PDF]

, 2015
Dissertação para obtenção do grau de Mestre no Instituto Superior de Ciências da Saúde Egas MonizNome completo da autora: Sara Filipa Vicente Mendes Pessoa de AlmeidaIntrodução: Os médicos de família e os pediatras estão na linha da frente na ...
Mendes, Sara
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Salivary Fluoride level in preschool children after toothbrushing with standard and low fluoride content dentifrice, using the transversal dentifrice application technique: pilot study [PDF]

RGO: Revista Gaúcha de Odontologia, 2008
Objective: To investigate the salivary fluoride concentration in pre-school children after toothbrushing with dentifrice containing standard (1100ppmF/NaF) and low (500ppmF/NaF) fluoride concentration, using the transversal technique of placing the ...
Fabiana Jandre Melo
doaj  

Problemática de las emisiones de flúor, cloro y azufre durante la cocción de materiales de la industria ladrillera. [PDF]

, 1998
proceso de cocción de materias primas cerámicas lleva implícito la emisión de elementos contaminantes (F, Cl, SO2, B, NOx ). En el caso de emisiones de F, Cl, y S la contaminación depende de la concentración de estos elementos en las materias primas ...
Fabbri, Bruno, Galán Huertos, Emilio, González Díez, María Isabel   +2 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Efecto de altas concentraciones de arsénico y flúor en el suelo sobre plantas de soja [PDF]

, 2015
Arsénico (As) y Fluor (F) están presentes en muchos suelos, afectando a los cultivos y presentando riesgos en la cadena alimenticia. Nosotros llevamos a cabo un experimento en macetas con suelo enriquecido en ambos elementos, en un amplio rango de ...
Balestrasse, Karina Beatriz, Bustingorri, Carolina, Lavado, Raul Silvio   +2 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source