Results 41 to 50 of about 328,735 (192)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Ciencia Veterinaria, 2017 La provincia de La Pampa (Argentina) se caracteriza por presentar en sus aguas subterráneas alta concentración de arsénico y flúor. En este trabajo, se determinó la concentración de flúor y arsénico en el agua de red que llega a los habitantes de la ...
Alberto Oscar Pariani +7 more
doaj
Biomédica: revista del Instituto Nacional de SaludIntroducción. La fluorosis dental es un problema endémico en el sur de Colombia, especialmente por su cercanía a zonas volcánicas y la composición de sus aguas. Objetivo.
Yeimy Tatiana Ortega +4 more
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Ten years of external control of the fluoride level in public drinking water provided by Brazilian cities, Brazil, 1996-2006 [PDF]
RGO: Revista Gaúcha de Odontologia, 2008 Objective: To evaluate the program of external control of water fluoridation performed in the periods between 1996 and 2006 by ten cities: eight in the State of São Paulo, one in Minas Gerais and another in the State of Ceará.
Jaime Aparecido Cury +4 more
doaj
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
INVESTIGAÇÃO DO USO DE POLIVITAMÍNICOS COMO POSSÍVEL CAUSA DE FLUOROSE EM CRIANÇAS
Colloquium Vitae, 2009 Este trabalho teve por objetivo investigar as causas da fluorose dando enfoque principal à presença de flúor nos polivitamínicos. Foram avaliadas crianças com fluorose coletando dados referente à história pregressa de utilização de fluoretos, como o uso ...
Eliane C Gava Pizi +2 more
doaj
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
FEBS Open Bio, EarlyView.We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source