Results 61 to 70 of about 338,159 (191)

Eefectividad de los colutorios de clorhexidina más flúor en niños de 6 años con alto riesgo de caries Effectiveness of the clorhexidine plus fluoride collutoriums in 6 year-old children with high risk of dental caries

Medisan, 2013
Se efectuó un estudio cuasiexperimental en 27 escolares de 6 años con alto riesgo de caries, pertenecientes a la Escuela Primaria "Miguel Ángel Oramas Alfonso" de Santiago de Cuba, desde octubre del 2009 hasta mayo del 2012, con vistas a determinar la ...
Ana Caridad López Vantour, Rodel Escalona Vega, Eugenia González Heredia, Ana Maria Quinzan Luna, Nelaine Ocaña Fontela   +4 more
doaj  

Comparison of the Photobleaching and Photostability Traits of Alexa Fluor 568- and Fluorescein Isothiocyanate- conjugated Antibody [PDF]

Cell Journal, 2011
Objective: Synthetic fluorescent dyes that are conjugated to antibodies are useful tools toprobe molecules. Based on dye chemical structures, their photobleaching and photostabilityindices are quite diverse.
Ahmad Reza Mahmoudi, Mohtaram Vafakhah, Elham Shaban, Reza Hadavi, Mahmood Jeddi-Tehrani, Ali Ahmad Bayat, Maryam Darzi, Majid Tarahomi, Roya Ghods, Jafar Mahmoudian   +9 more
doaj  

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra, Nagendra K. Rai, Timothy D. Niepokny, Haley Courtney, Ajai Tripathi, Ranjan Dutta   +5 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Synbiotic Characteristics of Soy Milk Curd for the Prevention of Pathological Fluor Albus in Female Adolescents

Health Dynamics
Introduction: Fluor albus is one of the problems that has long been a problem for women. Leucorrhea or Flour Albus is a symptom that most women very often experience. This disorder is the second most common problem after menstrual disorders. Fermentation
Rani Safitri, Rosyidah Alfitri, Nila Widya Keswara   +2 more
doaj   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

Bebidas embotelladas como fuentes adicionales de exposición a flúor

Salud Pública de México, 1998
Objetivo. Evaluar y notificar la concentración de fluoruro en bebidas embotelladas que se consumen en la ciudad de San Luis Potosí, S.L.P., México y su implicación como factor de riesgo a fluorosis dental. Material y métodos.
Loyola-Rodríguez Juan Pablo, Pozos-Guillén Amaury de Jesús, Hernández-Guerrero Juan Carlos   +2 more
doaj  

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

An Integrated Oxygen‐Supplying Device and Predictive Multiphysics Model for Extended Ambient Transport of Insulin‐Producing Cells

Advanced Functional Materials, EarlyView.
Cell therapies typically rely on cold‐chain logistics and cryopreservation, limiting access and compromising cell quality. Here, a dual‐chamber device separates an oxygen‐supplying chamber from a hyaluronic acid cargo chamber, sustaining oxygen delivery for over 70 h and enabling ambient‐temperature shipment.
Daniel A. Domingo‐Lopez, Ruth Tarpey, Benjamin Brennan, Bryan D. Boyle, Amir M. Alsharabasy, Abhik Mallick, Gabriella Bellavia, Abhay Pandit, Garry P. Duffy, Ruth E. Levey   +9 more
wiley   +1 more source

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source