Results 141 to 150 of about 99,089 (292)

Sodium-Dependent Conformational Change in Flagellar Stator Protein MotS from Bacillus subtilis

Biomolecules
The bacterial flagellar motor consists of a rotor and stator units and is driven by ion flow through the stator. The activation of the ion flow is coupled with the anchoring of the stator units to the peptidoglycan layer by the stator B-subunit around ...
Norihiro Takekawa, Ayaka Yamaguchi, Koki Nishiuchi, Maria Uehori, Miki Kinoshita, Tohru Minamino, Katsumi Imada   +6 more
doaj   +1 more source

First notice of Therion from South America with description of two new species from Argentina and Bolivia (Hymenoptera: Ichneumonidae) [PDF]

, 1999
Therion Curtis (Ichneumonidae: Anomalinae) has a nearly cosmopolitan geographic distribution but has not previously been recorded from South America. In most Therion the tarsal claws are simple or have only a few inconspicuous teeth near the base.
Porter, Charles C.
core  

The use of deidentified organ donor testes for research

Andrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova, Marnie W. Skinner, Juliana I. Candelaria, Stephen R. Wellard, Philip W. Jordan   +4 more
wiley   +1 more source

CRISPR/Cas9‐mediated Genome‐editing Reveals 10 Testis‐enriched Genes and One Non‐testis‐enriched Gene are Dispensable for Male Fecundity in Mice

Andrology, EarlyView.
ABSTRACT Background More than 1000 genes have been identified as predominantly expressed in the human testis. Advances in gene editing technologies have enabled the rapid and efficient generation of genetically engineered mice. This approach facilitates the screening of genes essential for spermatogenesis by analyzing knockout mouse models.
Yumiao Qiu, Keisuke Shimada, Masahito Ikawa   +2 more
wiley   +1 more source

Multiple Chaperone DnaK–FliC Flagellin Interactions are Required for Pseudomonas aeruginosa Flagellum Assembly and Indicate a New Function for DnaK

Microbial Biotechnology
The DnaK (Hsp70) protein is an essential ATP‐dependent chaperone foldase and holdase found in most organisms. In this study, combining multiple experimental approaches we determined FliC as major interaction partner of DnaK in the opportunistic bacterial
Gabriella Molinari, Sara S. Ribeiro, Katrin Müller, Benjamin E. Mayer, Manfred Rohde, Alejandro Arce‐Rodriguez, Juan José Vargas‐Guerrero, Albert Avetisyan, Josef Wissing, Werner Tegge, Lothar Jänsch, Mark Brönstrup, Antoine Danchin, Martina Jahn, Kenneth N. Timmis, Simon Ebbinghaus, Dieter Jahn, José Manuel Borrero‐de Acuña   +17 more
doaj   +1 more source

Microtubule Inner Protein CFAP77 Contributes to Sperm Motility and Male Fertility in Mice

Andrology, EarlyView.
ABSTRACT Background Sperm motility is essential for male fertility, and its regulation is dependent on the structural integrity of the axoneme. The axoneme consists of a conserved “9+2” microtubule arrangement and is supported by microtubule inner proteins. However, the functional significance of many microtubule inner proteins remains unclear.
Haoting Wang, Anh Hoang Pham, Mengjiao Luo, Masahito Ikawa, Haruhiko Miyata   +4 more
wiley   +1 more source

Unravelling the Roles of Bacterial Nanomachines Bistability in Pathogens’ Life Cycle

Microorganisms
Bacterial nanomachines represent remarkable feats of evolutionary engineering, showcasing intricate molecular mechanisms that enable bacteria to perform a diverse array of functions essential to persist, thrive, and evolve within ecological and ...
Romain Gory, Nicolas Personnic, Didier Blaha   +2 more
doaj   +1 more source

Pig Seminal Plasma Extracellular Vesicles Enhance Motility During Preservation of Epididymal Spermatozoa but Impair Capacitation and IVF Parameters

Andrology, EarlyView.
ABSTRACT Background Extracellular vesicles (EVs) produced by accessory sex glands play a key role in sperm functionality, influencing motility, viability, acrosome integrity, metabolic activity, and capacitation. Most studies on the effects of EVs on spermatozoa have focused on ejaculated spermatozoa, which have already been exposed to their own native
Ana Moya‐Fernández, Santa María Toledo‐Guardiola, Peter Silke, Sergio Navarro‐Serna, Carmen Matás   +4 more
wiley   +1 more source

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

Andrology, EarlyView.
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan, Nini Wei, Weiwei Ma, Mengting Hu, Bei Zhang, Li Gao, Chao Gao, Xiaoyu Yang, Yan Meng, Jiayin Liu, Yugui Cui   +10 more
wiley   +1 more source

Testis‐Enriched F‐Box Protein FBXO39 Is Important for Spermiogenesis and Male Fertility in Mice

Andrology, EarlyView.
ABSTRACT Background The SCF (Skp–Cullin–F‐box) complex is a major class of E3 ubiquitin ligases. F‐box proteins constitute the SCF complex and play a critical role in recognizing substrates for ubiquitination. In mice, several F‐box proteins, including FBXO36 and FBXO39, are predominantly expressed in testes.
Yuki Kaneda, Haruhiko Miyata, Masahito Ikawa   +2 more
wiley   +1 more source