Results 151 to 160 of about 80,987 (294)

Sperm Mitochondrial DNA Copy Number and Nuclear DNA Methylation Across Clinical and Non‐Clinical Preconception Cohorts

Andrology, EarlyView.
ABSTRACT Background Sperm mitochondrial DNA copy number is an emerging marker of male fertility, with elevated mtDNAcn associated with poor semen quality across various populations. Sperm DNA methylation has also been previously demonstrated to be negatively correlated with semen parameters in IVF cohorts.
Savni Sawant, Karolina Nowak, Amanda L. Paskavitz, Emily Houle, Ricardo P. Bertolla, Lidia Minguez‐Alarcon, Russ Hauser, J. Richard Pilsner   +7 more
wiley   +1 more source

Spatiotemporal Expression of ARRDC5 in Mammalian Spermatogenesis

Andrology, EarlyView.
ABSTRACT Background Spermiogenesis is the final phase of sperm development during which haploid round spermatids transform into specialized spermatozoa and occurs across distinct stages of sperm production in the seminiferous epithelium. Abnormalities in this process lead to malformations and an inability of sperm to fertilize eggs.
LeeLa D. Robinson, Jon M. Oatley
wiley   +1 more source

Male Mice Heterozygous for Protamine 1 and Protamine 2 Are Infertile, Displaying Sperm Damage and Retention of Protamine 2 Precursors, Transition Proteins, and Histones

Andrology, EarlyView.
ABSTRACT Background During spermiogenesis, protamines (PRMs) replace histones to hypercondense and protect sperm DNA. Rodents and primates express two PRMs (PRM1 and PRM2). Alterations of species‐specific PRM ratios are associated with sub‐ or infertility in mice and humans.
Gina Esther Merges, Christoph Wiesejahn, Mar Domingo‐Lopez, Simon Schneider, Andjela Kovacevic, Lena Arévalo, Hubert Schorle   +6 more
wiley   +1 more source

Marginal Changes in Semen Quality Over Three Decades (1996‒2022) Among 8320 Men in the Danish Young Men Study (DYMS): Cohort Profile and Trends

Andrology, EarlyView.
ABSTRACT Background Since the 1990s, declining sperm counts and increasing testicular cancer rates have raised worldwide concern about male reproductive health, including in Denmark. This prompted a prospective population‐based study with annual surveillance of semen quality.
Lærke Priskorn, Cille Baslund‐Storch, Laura S. Hansen, Astrid L. Beck, Ann H. Hansen, Stine A. Holmboe, Loa Nordkap, Anne Kirstine Bang, Rune Lindahl‐Jacobsen, Christine Dalgård, Anna‐Maria Andersson, Tina K. Jensen, Anders Juul, Niels Jørgensen   +13 more
wiley   +1 more source

Lactate‐Responsive Glycogen Dynamics Are Associated With Bull Sperm Motility and Fertilization Under Glucose‐Limited Conditions

Andrology, EarlyView.
ABSTRACT Background Mammalian sperm need to undergo hyperactivation, capacitation, and acrosome reaction to achieve fertilization competence. However, the female reproductive tract presents contrasting metabolic environments. The uterus is glucose‐rich, and the oviduct is lactate‐rich and glucose‐limited.
Md Faizul Hossain Miraz, Takahiro Yamanaka, Takashi Umehara, Shahrina Akter, Wambugu Enoc Njoroge, Masayuki Shimada   +5 more
wiley   +1 more source

Multiple Chaperone DnaK–FliC Flagellin Interactions are Required for Pseudomonas aeruginosa Flagellum Assembly and Indicate a New Function for DnaK

Microbial Biotechnology
The DnaK (Hsp70) protein is an essential ATP‐dependent chaperone foldase and holdase found in most organisms. In this study, combining multiple experimental approaches we determined FliC as major interaction partner of DnaK in the opportunistic bacterial
Gabriella Molinari, Sara S. Ribeiro, Katrin Müller, Benjamin E. Mayer, Manfred Rohde, Alejandro Arce‐Rodriguez, Juan José Vargas‐Guerrero, Albert Avetisyan, Josef Wissing, Werner Tegge, Lothar Jänsch, Mark Brönstrup, Antoine Danchin, Martina Jahn, Kenneth N. Timmis, Simon Ebbinghaus, Dieter Jahn, José Manuel Borrero‐de Acuña   +17 more
doaj   +1 more source

A CCNA1 Missense Variant Associated With Chromatid Non‐Disjunction in Abnormal‐Headed Sperm and Male Infertility

Andrology, EarlyView.
ABSTRACT Background Macrozoospermia is a rare form of teratozoospermia characterized by tetraploids, large‐headed spermatozoa with multiple flagella, usually caused by bi‐allelic AURKC mutations. The etiology of atypical phenotypes with a lower proportion of large headed spermatozoa and single flagella however often remains unresolved.
Aurore Perrin, Frédéric Morel, Zeina Wehbe, Cynthia Frapsauce, Nadia Gueganic, Corinne Tous, Séverine Commet, Laura Dijols, Audrey Basinko, Nathalie Douet‐Guilbert, Célia Tebbakh, Zine‐Eddine Kherraf, Pierre F. Ray, Charles Coutton, Guillaume Martinez   +14 more
wiley   +1 more source

The Intriguing History of Gloves and Their Application to Surgery

ANZ Journal of Surgery, EarlyView.
Gloves were first worn to protect against cold and injury. In surgery, their purpose now is to reduce surgical site infection and blood‐borne transmission of disease. Surprisingly, their adoption in surgery as a routine has been remarkably recent and had a bizarre origin.
Spencer W. Beasley
wiley   +1 more source

Anatomical and Histological Structures of the Male Reproductive System of Chalcophora mariana (Linnaeus, 1758) (Coleoptera: Buprestidae): Light and Scanning Electron Microscopy Study

Acta Zoologica, EarlyView.
ABSTRACT This study presents the first detailed morphological analysis of the male reproductive system of Chalcophora mariana (Linnaeus, 1758) using stereo microscopy, light microscopy, and scanning electron microscopy. The male reproductive system of C.
Hicret Arslan, Selami Candan
wiley   +1 more source

Anatomical and Histological Descriptions of the Male Reproductive System of the Alfalfa Weevil of Hypera postica (Gyllenhal, 1813) (Coleoptera: Curculionidae) Using Light and Scanning Electron Microscopies

Acta Zoologica, EarlyView.
ABSTRACT Features of the reproductive organs, such as the number of testicular follicles, testis colour and the morphology of the glands, can be used as systematic characters. For this purpose, this paper was the first description of the male reproductive system anatomy and histology of Hypera postica (Gyllenhal, 1813) (Coleoptera: Curculionidae), a ...
Nurcan Özyurt Koçakoğlu, Selami Candan, Hicret Arslan, Mustafa Güllü   +3 more
wiley   +1 more source