Results 181 to 190 of about 39,486 (294)

Multicenter experience using tofacitinib for treatment of refractory pediatric inflammatory bowel diseases in the United States

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Tofacitinib is a selective Janus kinase (JAK‐1) inhibitor approved for the treatment of ulcerative colitis (UC) in adults. Data is limited in the pediatric population. The aim of this study was to evaluate the efficacy of tofacitinib in pediatric inflammatory bowel disease (IBD).
Denise D. Young, Jennifer E. Murphy, Mallory Chavannes, Jennifer L. Dotson, Jeanne Tung, Erica Chang, Brad Pasternak, Erin Crawford, Nancy McGreal, Jonathan Moses, Sandra C. Kim   +10 more
wiley   +1 more source

Correlation between active regions' spectra at high radio frequencies and solar flare occurrences. [PDF]

Sci Rep
Mulas S, Pellizzoni A, Marongiu M, Marcucci A, Righini S, Iacolina MN, Egron E, Murtas G, Bachetti M, Berrilli F, Cabras A, Caocci R, Deiana GL, Guglielmino SL, Haggerty C, Ladu A, Loru S, Maccaferri A, Marongiu P, Melis A, Navarrini A, Orfei A, Ortu P, Pili M, Pisanu T, Pupillo G, Saba A, Schirru L, Serra G, Tiburzi C, Valente G, Zanichelli A, Zucca P, Messerotti M.   +33 more
europepmc   +1 more source

Essential and toxic elements intake from botanical extracts: a probabilistic risk–benefit evaluation within the Italian dietary context

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Botanical extracts are widely consumed for their claimed health benefits, yet their safety profile with respect to chronic consumption remains poorly characterized. Understanding the potential health risks associated with their inorganic content is a crucial issue for ensuring safe use, along with a characterization of the ...
Giovanni Tommaso Lanza, Maria Olga Varrà, Lenka Husáková, Martina Piroutková, Jan Patočka, Emanuela Zanardi   +5 more
wiley   +1 more source

Tracking clonal dynamics of CD8 T cells and immune dysregulation in progression of systemic lupus erythematosus with nephritis. [PDF]

Exp Mol Med
Paek SJ, Lee HS, Lee YJ, Bang SY, Kim D, Kang BK, Park DJ, Joo YB, Kim M, Kim H, Park SY, Park WY, Abe T, Itamiya T, Nagafuchi Y, Ishigaki K, Fujio K, Kim KT, Bae SC.   +18 more
europepmc   +1 more source

A Potassium-Flare Star.

The Astrophysical Journal, 1962
Daniel Barbier, Nina Morguleff
openaire   +1 more source

Prevalence and Burden of Somatic Symptom Disorder in Atopic Dermatitis and Chronic Pruritus—The Persistent Somatic Symptoms Across Diseases: Pruritus (SOMA.PRU) Study

JEADV Clinical Practice, EarlyView.
In adults with atopic dermatitis and chronic pruritus, the mental comorbidity of Somatic Symptom Disorder is associated with higher average and worst pruritus intensity, higher psychological distress and lower quality of life. Additionally, there were nonsignificant changes in cutaneous nerve fiber densities in skin biopsies.
Stefan M. Kahnert, Ansgar Koechel, Gina L. Frank, Svenja Royeck, Claudia Zeidler, Felix Witte, Christian Mess, Konstantin Agelopoulos, Volker Huck, Bernd Löwe, Rupert Conrad, Gudrun Schneider, Stefan W. Schneider, Sonja Ständer   +13 more
wiley   +1 more source

Adaptive Optics Imaging Uncovers Photoreceptor Alterations Underlying Visual Distortion After Cystoid Macular Edema. [PDF]

J Vitreoretin Dis
Khoussine J, Arthur P, Rogers J, Stangel N, Stepien KE, Chang JS.   +5 more
europepmc   +1 more source

A Case of Pembrolizumab‐Induced Pityriasis Lichenoides‐Like Eruption Treated Successfully With Dupilumab

JEADV Clinical Practice, EarlyView.
ABSTRACT Immune‐checkpoint inhibitors (ICIs) have revolutionised melanoma treatment but can often cause severe and long‐standing cutaneous immune‐related adverse events (cirAEs). We report a case of refractory pembrolizumab‐induced pityriasis lichenoides (PL)‐like eruption successfully treated with dupilumab, leading to rapid and sustained remission ...
Evangelos Christou, Sharon Edwards, Andrew Affleck   +2 more
wiley   +1 more source

Long-term outcomes of JIA-associated uveitis: a systematic review and meta-analysis. [PDF]

RMD Open
Scagnellato L, Cozzi G, Lorenzin M, Poncina G, Rizzetto S, Ramonda R.   +5 more
europepmc   +1 more source

Surgical Procedures and Medical Treatments Among Patients With Hidradenitis Suppurativa Before and After Referral to Specialised Dermatological Hospital Care: A Nationwide Registry Study

JEADV Clinical Practice, EarlyView.
Hidradenitis suppurativa (HS) is often diagnosed late, complicating management. In this nationwide Danish study including 10,196 patients with dermatologist‐verified HS, we examined treatment patterns before and after referral to specialised hospital care.
Nana A. L. Rosenø, Nadja Højgaard Pedersen, Yvonne Geissbühler, Nikolaj Holgersen, Valdemar Wendelboe Nielsen, Jacob P. Thyssen, Alexander Egeberg, Hans Christian Ring, Simon Francis Thomsen   +8 more
wiley   +1 more source