Results 231 to 240 of about 442,397 (295)

The Use of Topical Tacrolimus as Adjunct Therapy to Corticosteroid in a High-Risk Penetrating Keratoplasty: A Systematic Review and Meta-Analysis. [PDF]

J Curr Ophthalmol
Advani MS, Widyawati S.
europepmc   +1 more source

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

Pediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

A Single-Chain Light-Activatable Transcriptional Reporter for Fluorescently Tagging Mammalian Cells In Vitro. [PDF]

Chembiochem
Bartolik O, Wang W.
europepmc   +1 more source

Mirikizumab pharmacokinetics and exposure–response in pediatric patients with moderate‐to‐severe ulcerative colitis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 474-485, March 2025.
Abstract Mirikizumab is a p19‐directed anti‐interleukin‐23 antibody approved for the treatment of adults with moderate‐to‐severe ulcerative colitis (UC). Here, we report the first data of mirikizumab pharmacokinetics (PK) and exposure–response (E/R) relationships in pediatric participants (aged 2 to <18 years weighing >10 kg) with moderate‐to‐severe UC
Yuki Otani, Laiyi Chua, Wendy J. Komocsar, Amy Larkin, Jordan Johns, Xin Zhang   +5 more
wiley   +1 more source

Physiological Data Collected From Wearable Devices Identify and Predict Inflammatory Bowel Disease Flares. [PDF]

Gastroenterology
Hirten RP, Danieletto M, Sanchez-Mayor M, Whang JK, Lee KW, Landell K, Zweig M, Helmus D, Fuchs TJ, Fayad ZA, Nadkarni GN, Keefer L, Suarez-Farinas M, Sands BE.   +13 more
europepmc   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

Co-Designing Mobile Serious Games to Support Patients With Psoriatic Arthritis and Chronic Pain: Mixed Methods Study. [PDF]

JMIR Serious Games
Ramalho B, Gomes S, Silva Vicente M, Magalhães F, Gonçalves Costa R, Gama S, Charisis V, Hadjileontiadis L, B Dias S, iPROLEPSIS Consortium.   +9 more
europepmc   +1 more source

Pharmacokinetic and Pharmacodynamic Interactions Between Anti‐Asthma Drugs and Medicinal Plants: A Comprehensive Review

Phytotherapy Research, EarlyView.
ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit, Aylin Bülbül, Betul Kocaadam‐Bozkurt, Osman Bozkurt, Duygu Ağagündüz, Raffaele Capasso   +5 more
wiley   +1 more source

Isotopic evidence for a cold and distant origin of 3I/ATLAS. [PDF]

Nature
Cordiner M, Roth NX, Micheli M, Villanueva G, Farnocchia D, Charnley S, Biver N, Bockelée-Morvan D, Bodewits D, Chandler CO, Crovisier J, Drozdovskaya MN, Furuya K, Kelley MSP, Milam S, Noonan JW, Opitom C, Schwamb ME, Thomas CA.   +18 more
europepmc   +1 more source

High‐Dimensional Cumulative Sum Control Charts for Industrial Measurement Systems

Quality and Reliability Engineering International, EarlyView.
ABSTRACT High dimensional sensing in modern factories and energy assets produces thousands of correlated signals. Detecting small process shifts is challenging because many classical multivariate charts lose power or become unstable. We present two cumulative sum procedures for two sample monitoring that remain effective when the number of variables is
Osama Alhadi, Tahir Mahmood, Muhammad Riaz, Nasir Abbas   +3 more
wiley   +1 more source