Results 51 to 60 of about 389,346 (315)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Proton boron capture therapy: microdosimetry and treatment planning study with boron

open access: yesFrontiers in Oncology
BackgroundProton-boron capture therapy (PBCT) has been proposed as a method to enhance the biological effectiveness of proton therapy through the p + 11B → 3α nuclear reaction.
Seung Hoon Yoo   +17 more
doaj   +1 more source

First Evidence of Temporary Read Errors in TLC 3D-NAND Flash Memories Exiting From an Idle State

open access: yesIEEE Journal of the Electron Devices Society, 2020
This paper presents a new reliability threat that affects 3D-NAND Flash memories when a read operation is performed exiting from an idle state. In particular, a temporary large increase of the fail bits count is reported for the layers read as first ...
Cristian Zambelli   +3 more
doaj   +1 more source

The Green Flash [PDF]

open access: yesJournal of General Internal Medicine, 2007
It was luck I was there on a Sunday when Mr. H.’s son (the drunk, also my clinic patient) shouted at a nurse that his father was dead. I went to see (the nurse didn’t). H. was inanimate as a wind-up toy run-out in mid-stride, his foot sticking out from under the sheet barely warm and weirdly doughy. The son came in then (I think)
openaire   +2 more sources

Using Adobe Flash Lite on mobile phones for psychological research: reaction time measurement reliability and inter-device variability [PDF]

open access: yes, 2008
Mobile telephones have significant potential for use in psychological research, possessing unique characteristics—not least their ubiquity—that may make them useful tools for psychologists.
Stewart, Neil, Reimers, Stian
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Pengembangan Aplikasi Android Sebagai Media Pembelajaran Alat Transportasi

open access: yesJurnal Sarjana Teknik Informatika, 2020
Perkembangan teknologi memudahkan anak-anak untuk menerima berbagai infomasi. Salah satunya perangkat mobile yaitu smartphone Android. Smartphone dapat membantu dalam poses pembelajaran anak-anak. Seperti pengenalan alat transportasi.
Ardian Dwi Prasetyo
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Flash: The International Short-Short Story Magazine, 12.1 (April 2024) [PDF]

open access: yes
Founded 2008, Flash: The International Short-Short Story Magazine is a biannual literary periodical publishing flash fictions of up to 360 words.N/
Various
core   +3 more sources

Flash Crowd Detection within the realms of an Internet Service Provider (ISP) [PDF]

open access: yes, 2008
It is truly a challenge to detect a network phenomenon with an unpredictable persona. Due to the simultaneous dependency on network traffic and end users, events such as Flash Crowds are hard to predict.
Hutchison, D.   +4 more
core  

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