Results 151 to 160 of about 20,723,496 (219)

Repurposed catechol‐O‐methyltransferase inhibitors tolcapone and entacapone preferentially suppress aggregation and seeding of P301 mutant tau in human neuronal models

British Journal of Pharmacology, EarlyView.
Background and purpose Pathogenic aggregation and propagation of seed‐competent TAU assemblies drive tauopathies. MAPT P301 mutations accelerate aggregation and enhance seed competence, yet pharmacological strategies selectively targeting these pathogenic species remain limited.
Ihor Kozlov, Yu‐Sheng Hung, Sudeep Roy, Alladi Charanraj Goud, Roman Kouřil, Yu‐Hui Wong, Viswanath Das   +6 more
wiley   +1 more source

Flash glucose monitoring system: impact on glycemic control and body mass index in type 1 diabetes mellitus. [PDF]

Arch Endocrinol Metab, 2021
Sá JM, Lopes SC, Barbosa M, Barros IF, Santos MJ.   +4 more
europepmc   +1 more source

GLP‐1 receptor activation attenuates chronic migraine‐like behaviour: Sex‐specific modulation of opioid‐ and endocannabinoid‐related pathways

British Journal of Pharmacology, EarlyView.
Background and Purpose Chronic migraine (CM) is a highly disabling condition that remains suboptimally treated. Metabolic disturbances may trigger migraine chronification, whereas impaired endogenous pain inhibition contributes to CM development. Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs), used for type 2 diabetes and obesity, show efficacy ...
Katarina Sićović, Katarina Nastić, Miroslav Dinić, Emilija Brdarić, Uroš Pecikoza, Maja Tomić, Ana Micov   +6 more
wiley   +1 more source

Clustering of technological attitudes and reasons for device (non‐)uptake among Dutch people with type 1 diabetes, family members and health professionals

Diabetic Medicine, EarlyView.
Abstract Background Pump and sensor technology contributes to glucose management and quality of life for people with type 1 diabetes (PWD). However, not everyone uses these technologies. This commonly relates to technological attitudes, experiences and expectations. Also, parents and partners (P/P) and healthcare providers (HCPs) may impactful decision‐
M. Horsselenberg, J. B. Prins, M. Boenink, H. J. Aanstoot, G. Nefs   +4 more
wiley   +1 more source

Evaluation for the feasibility and accuracy of Freestyle Libre Flash Glucose Monitoring System used by COVID-19 patients in intensive care unit. [PDF]

J Diabetes, 2021
Zhang Y, Liu X, Zhang J, Fu J, Li S, Chen S, Chen Y, Lu B.   +7 more
europepmc   +1 more source

The Performance of Freestyle Libre Pro Flash Continuous Glucose Monitoring in Hospitalized Patients Treated with an Intravenous Insulin Infusion for Acute Prednisolone-Induced Hyperglycemia

Few studies have evaluated the performance of flash glucose monitoring in hospitalized patients requiring intravenous insulin therapy. In this prospective study, an intravenous insulin infusion was adjusted hourly using flash glucose monitoring in ...
Zimmermann, A., Stranks, S.N., Chen, A.X., Radhakutty, A., Thompson, C.H., Burt, M.G.   +5 more
core   +1 more source

The national implementation of ‘Healthy Living’, a web‐based type 2 diabetes self‐management education and support service: Narrative synthesis of evaluation findings and implications for service delivery and research

Diabetic Medicine, EarlyView.
Abstract Aims NHS England adopted ‘HeLP‐Diabetes’, a web‐based diabetes self‐management and education service, effective in a clinical trial and implemented it across England as ‘Healthy Living for people with type 2 diabetes’ (Healthy Living). This paper aims to narratively synthesise findings from a programme of mixed‐methods evaluations undertaken ...
Sarah Cotterill, Rhiannon E. Hawkes, Martin K. Rutter, Rachel A. Elliott, Evangelos Kontopantelis, Luke Paterson, Salwa S. Zghebi, Lisa Brunton, Jack S. Benton, Antonia M. Marsden, Brian McMillan, Eric Lowndes, Caroline Sanders, Paul Wilson, David P. French   +14 more
wiley   +1 more source

Capability, opportunity and motivation to support adults with type 1 diabetes experiencing fear of hypoglycaemia: A survey of Australian diabetes healthcare professionals

Diabetic Medicine, EarlyView.
Abstract Aim To explore the perceptions, experiences and unmet needs of diabetes healthcare professionals (DHPs) for supporting adults with type 1 diabetes (T1D) with fear of hypoglycaemia (FoH). Method An online survey explored Australian DHPs' perceived capability, opportunity, motivation and behaviours related to supporting adults with T1D with FoH.
Uffe Søholm, Jennifer Halliday, Elizabeth Holmes‐Truscott, Virginia Hagger, Alison Robinson, Caitlin Rogers, Christian Criado‐Perez, Sienna Russell‐Green, Sofianos Andrikopoulos, James A. M. Shaw, Jane Speight, on behalf of the HypoPAST Study Group, Jane Speight, Christel Hendrieckx, Timothy C. Skinner, James A. M. Shaw, Sophia Zoungas, Cathrine Mihalopoulos, Vincent L. Versace, Elizabeth Holmes‐Truscott, Virginia Hagger, Renza Scibilia, Sof Andrikopoulos, Taryn Black, Susan Davidson, Glen Noonan, Jennifer Halliday, Shaira Baptista, Mary Lou Chatterton, Eric O., Chatpakorn Prasertsung, Alison Robinson, Sienna Russell‐Green, Uffe Søholm, Sharmala Thuraisingam   +34 more
wiley   +1 more source

Evaluation of low and high interstitial glucose concentrations in healthy, nondiabetic dogs using a flash glucose monitoring system. [PDF]

J Vet Intern Med
Brisman RF, Palma DA, Fox PR.
europepmc   +1 more source