Results 171 to 180 of about 20,723,496 (219)

RNF13 regulates the endolysosomal pathway through interaction with the small GTPase Arl8B

The FEBS Journal, EarlyView.
The E3 ubiquitin ligase RNF13 functions as a regulatory scaffold, organizing Arl8B‐dependent complexes and tuning downstream signaling that controls endolysosomal organization and trafficking. In this model, wild‐type RNF13 associates with Arl8B on endolysosomes, whereas Arl8B (E22D/F55A) or RNF13 (L244A) variants weaken complex assembly, potentially ...
Audrey M. Sénécal, Valérie C. Cabana, Antoine Y. Bouchard, Laurent Cappadocia, Marc P. Lussier   +4 more
wiley   +1 more source

Efficacy and safety of needle-free injection in patients with type 2 diabetes mellitus undergoing intensive insulin therapy: a randomized controlled trial based on the flash glucose monitoring system. [PDF]

Front Endocrinol (Lausanne)
Wang J, Liu Z, Jiao L, Zhou J, Wang T, Li C, Wang Q, Yuan L, Zhang F, Li G, Zhu Q, Jin S, Zhang L.   +12 more
europepmc   +1 more source

Circadian rhythms of metabolite abundance in Drosophila are largely driven by time of feeding

The FEBS Journal, EarlyView.
Circadian clocks exist in the brain and peripheral tissues such as the Drosophila fat body. Single‐nuclei transcriptomics reveal that the fat body clock generates time‐of‐day differences in metabolic gene transcription, which may also be indirectly controlled by brain clocks.
Sumit Saurabh, Charlene Y. P. Guerrero, Madelyn R. Cusick, Amanda J. Samaras, Taylor M. Stephenson, Sebastian L. Kirkpatrick, Gregory J. Matthews, Daniel J. Cavanaugh   +7 more
wiley   +1 more source

Assessment of FreeStyle Libre Flash Glucose Monitoring System Implementation in Real Life Clinical Setting: A Prospective Observational Study. [PDF]

Diagnostics (Basel), 2021
Canecki Varzic S, Steiner K, Gradinjan Centner M, Grgurevic M, Cigrovski Berkovic M, Klobucar Majanovic S, Radman M, Milicevic T, Rahelic D, Bilic Curcic I.   +9 more
europepmc   +1 more source

Crystal structure of human NIF3‐like protein reveals dynamic hexameric assembly with a single divalent metal binding site

The FEBS Journal, EarlyView.
We present the first crystal structures of human NIF3, revealing a dynamic, hexameric ring with a central cavity regulated by flexible insertion domains. Crucially, human NIF3 features a mononuclear zinc‐binding site, marking a distinct evolutionary departure from the dinuclear centers of bacterial homologs.
Elżbieta Wątor‐Wilk, Krzysztof Żak, Piotr Wilk, Paweł Kochanowski, Agnieszka Maślanka, Łukasz Skalniak, Przemysław Grudnik   +6 more
wiley   +1 more source

A comprehensive study on ferredoxin isoforms in the cyanobacterium Synechocystis sp. PCC 6803

The FEBS Journal, EarlyView.
Ferredoxins are small FeS cluster‐containing proteins that play a central role in distributing electrons within the cell. The cyanobacterium Synechocystis sp. PCC 6803 contains several ferredoxin isoforms and their biophysical properties (UV/Vis and EPR spectra, Em potential), expression patterns, and interactions with the electron donors photosystem I
Marko Boehm, Drazenka Svedruzic, Carolyn E. Lubner, Jens Appel, David W. Mulder, Effie C. Kisgeropoulos, Vanessa Hueren, Katharina Spengler, Vivek S. Bharadwaj, Zhanjun Guo, Anastasia E. Ledinina, Darja Deobald, Lorenz Adrian, Paul W. King, Kirstin Gutekunst   +14 more
wiley   +1 more source

Acute freshwater CO2 exposure does not impair seawater transfer in three different sizes of Atlantic salmon (Salmo salar) subjected to different photoperiod manipulations

Journal of Fish Biology, EarlyView.
Abstract There is a growing interest in Atlantic salmon (Salmo salar) aquaculture to extend the time fish are reared in freshwater (FW) recirculating aquaculture systems (RAS), producing larger FW salmon that can then be induced to undergo smoltification before transfer into marine net pens for grow‐out and harvest.
Le Thi Hong Gam, Daniel W. Montgomery, Daniel S. Laronde, Rachael Mackinnon, Jeffrey G. Richards, Colin J. Brauner   +5 more
wiley   +1 more source

Metabolic Adaptations to Weight Loss in Obese Senior Dogs: Effects on Energy Expenditure, Protein Turnover, and Voluntary Physical Activity

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Implications of obesity and weight loss (WL) for energy and protein metabolism are not fully understood, particularly in senior dogs. This study evaluated changes in body composition, energy expenditure (EE), protein turnover (PT), and voluntary physical activity (VPA) in senior dogs in maintenance and after 10% and 20% WL.
Ticiane Giselle Bitencourt Freire, Jhennifer de Castro Fenerick, Ariel de Castro, Maria Eduarda Gonçalves Tozato, Stephanie de Souza Theodoro, Letícia Grazielle Pacheco, Camila Goloni, Caroline Paschoal, Vladimir Eliodoro Costa, Aulus Cavalieri Carciofi   +9 more
wiley   +1 more source

Concurrent Measurement of O2 Production and Isoprene Emission During Photosynthesis: Pros, Cons and Metabolic Implications of Responses to Light, CO2 and Temperature

Plant, Cell &Environment, EarlyView.
ABSTRACT Traditional leaf gas exchange experiments have focused on net CO2 exchange (Anet). Here, using California poplar (Populus trichocarpa), we coupled measurements of net oxygen production (NOP), isoprene emissions and δ18O in O2 to traditional CO2/H2O gas exchange with chlorophyll fluorescence, and measured light, CO2 and temperature response ...
Kolby Jeremiah Jardine, Suman Som, Luiza Beraldi Gallo, Jilian Demus, Tomas Ferreira Domingues, Christina Marie Wistrom, Lianhong Gu, Guillaume Tcherkez, Ülo Niinemets   +8 more
wiley   +1 more source

Clinical Performance of Flash Glucose Monitoring System in Patients with Liver Cirrhosis and Diabetes Mellitus. [PDF]

Sci Rep, 2020
Costa D, Lourenço J, Monteiro AM, Castro B, Oliveira P, Tinoco MC, Fernandes V, Marques O, Gonçalves R, Rolanda C.   +9 more
europepmc   +1 more source