Results 71 to 80 of about 128,247 (281)
Solutions to the Quasi-flatness and Quasi-lambda Problems [PDF]
, 1999 Big Bang models of the Universe predict rapid domination by curvature, a paradox known as the flatness problem. Solutions to this problem usually leave the Universe exactly flat for every practical purpose.
Bekenstein +3 more
core +2 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Subpullbacks and coproducts of $S$-posets [PDF]
Categories and General Algebraic Structures with Applications, 2015 In 2001, S. Bulman-Fleming et al. initiated the study of three flatness properties (weakly kernel flat, principally weakly kernel flat, translation kernel flat) of right acts $A_{S}$ over a monoid $S$ that can be described by means of when the functor ...
Xingliang Liang, Yanfeng Luo
doaj
Rapid Inspection of Large Concrete Floor Flatness Using Wheeled Robot with Aided-INS
Remote Sensing, 2022 Flatness is an important parameter for the quality assessment of concrete floors. Traditional flatness inspection methods have problems with sparse sampling and low efficiency for large concrete floors.
Zhipeng Chen +6 more
doaj +1 more source
Varying c and Particle Horizons [PDF]
, 2001 We explore what restrictions may impose the second law of thermodynamics on varying speed of light theories. We find that the attractor scenario solving the flatness problem is consistent with the generalized second law at late time.Comment: Latex file ...
Albrecht +33 more
core +3 more sources
Journal of Algebra, 1995 Let \(f : (X,x) \to (Y,y)\) be a morphism of local schemes and \((Z,x)\) the central fiber. The flatness of \(f\) is a subtle geometric notion and it is difficult to find some flatness criteria which do not require infinitesimal properties. A well-known result of \textit{H. Hironaka} [Ill. J. Math.
openaire +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Anomalies, D-flatness and Small Instantons
, 1995 Recently, Witten has proposed a mechanism for symmetry enhancement in $SO(32)$ heterotic string theory, where the singularity obtained by shrinking an instanton to zero size is resolved by the appearance of an $Sp(1)$ gauge symmetry. In this short letter,
Alvarez-Gaumé +12 more
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
On quantum state of numbers [PDF]
, 2013 We introduce the notions of quantum characteristic and quantum flatness for arbitrary rings. More generally, we develop the theory of quantum integers in a ring and show that the hypothesis of quantum flatness together with positive quantum ...
Quirós, Adolfo, Stum, Bernard Le
core +1 more source