Results 91 to 100 of about 787,641 (342)
Stationary solutions and asymptotic flatness II [PDF]
This is the second part of the investigation started in [Stationary solutions and asymptotic flatness I]. We prove here that Strongly Stationary ends having cubic volume growth are Weakly Asymptotically Flat.
Reiris, Martin
core +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Difficult-to-cut titanium matrix composites (TMCs) are widely used in the aerospace, automotive, and defense sectors due to their excellent physical properties.
Shen Niu +4 more
doaj +1 more source
On quantum state of numbers [PDF]
We introduce the notions of quantum characteristic and quantum flatness for arbitrary rings. More generally, we develop the theory of quantum integers in a ring and show that the hypothesis of quantum flatness together with positive quantum ...
Quirós, Adolfo, Stum, Bernard Le
core +1 more source
The flatness problem and $\Lambda$
By way of a complete integration of the Friedmann equations, in terms of observables, it is shown that for the cosmological constant $\Lambda > 0$ there exist non-flat FLRW models for which the total density parameter $\Omega$ remains $\sim 1$ throughout
A. G. Riess +7 more
core +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Subpullbacks and coproducts of $S$-posets [PDF]
In 2001, S. Bulman-Fleming et al. initiated the study of three flatness properties (weakly kernel flat, principally weakly kernel flat, translation kernel flat) of right acts $A_{S}$ over a monoid $S$ that can be described by means of when the functor ...
Xingliang Liang, Yanfeng Luo
doaj
From Planck to GUT via Dimensional Transmutation [PDF]
Consider a gauge singlet superfield S coupled to a pair of adjoint fields in a SUSY-GUT. If the tree-level vacuum is flat in S, the vev which defines the GUT scale will be determined via dimensional transmutation at a scale M where the soft-breaking ...
Abbott +33 more
core +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source

