Results 101 to 110 of about 787,641 (342)

Criteria for flatness and injectivity

, 2011
Let $R$ be a commutative Noetherian ring. We give criteria for flatness of $R$-modules in terms of associated primes and torsion-freeness of certain tensor products.
A.S. Richardson, D. Kirby, E. Kunz, E. Matlis, E. Matlis, H. Zöschinger, I. Kaplansky, I.M. Aberbach, K. Divaani-Aazar, L. Angeleri Hügel, L. Chambless, L. Fuchs, L.L. Avramov, Neil Epstein, R.Y. Sharp, S. Yassemi, S. Yassemi, Yongwei Yao   +17 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Configuration Flatness of Lagrangian Systems Underactuated by One Control [PDF]

, 1996
Lagrangian control systems that are differentially flat with flat outputs that only depend on configuration variables are said to be configuration flat.
Murray, Richard M., Rathinam, Muruhan
core   +5 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Development and Validation of an Affordable Calibration Method for Surface Plates

Ingeniería e Investigación
The measurement and calibration of flat surfaces is highly relevant for precision engineering, length metrology, and optical systems. Hence, many National Metrology Institutes (NMIs) tend to offer calibration services in this regard.
Daniela Garzón, Jorge Luis Galvis Arroyave, David Plazas, Victor Hugo Gil, Ovidio Almanza   +4 more
doaj   +1 more source

The nonholonomic Riemann and Weyl tensors for flag manifolds [PDF]

, 2005
On any manifold, any non-degenerate symmetric 2-form (metric) and any skew-symmetric (differential) form W can be reduced to a canonical form at any point, but not in any neighborhood: the respective obstructions being the Riemannian tensor and dW.
Dimitry A. Leites, Dimitry Leites, Pavel Grozman, Pavel Grozman, The Nonholonomic Riemann, Weyl Tensors   +5 more
core   +1 more source

On Asymptotic Flatness and Lorentz Charges

, 2011
In this paper we establish two results concerning four-dimensional asymptotically flat spacetimes at spatial infinity. First, we show that the six conserved Lorentz charges are encoded in two unique, distinct, but mutually dual symmetric divergence free ...
Compère, Geoffrey, Dehouck, François, Virmani, Amitabh   +2 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source