Results 61 to 70 of about 4,683 (221)

Probing Cinnamamides and Benzamides as Anthelmintics: Discovery of Potent Drug‐Like Agents Against Angiostrongylus cantonensis

Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
Cynnamoyl benzylpiperazine was identified as drug‐like derivative of cinnarizine with anthelmintic activity against A. cantonensis. In this work, 15 out of 31 derivatives showed improved anthelmintic activity with increased solubility. A SAR study was carried out to determine the molecular features involved in such effect.
Bruna L. Lemes, Mariana A. Siegl‐Breno, Marina T. Varela, Flavia B. Lopes, Mikaelly K. Silva‐Nunes, Thaiane D. Santos, Lucas Fukui‐Silva, Daniel B. Roquini, Vinicius G. Maltarollo, Josué de Moraes, João Paulo S. Fernandes   +10 more
wiley   +1 more source

Comparison of free-living and parasitic flatworm Cys-Loop Ligand Gated Ion Channels (LGICs).

, 2019
(A) Cys-loop LGICs were curated from the genomes of a non-flatworm lophotrochozoan (A. californica) as well as free-living (M. lignano, S. mediterranea) and parasitic flatworms (E. multilocularis, C. sinensis, O. viverrini, S. haematobium, S.
V. V. N. Phani Babu Tiruveedhula (7871759), Brian C. Smith (2230093), Md Yeunus Mian (7871753), Farjana Rashid (7871762), Guanguan Li (2733235), Ranjit S. Verma (4914442), Lalit Kumar Golani (7871765), John D. Chan (7871768), James M. Cook (120501), Michael D. Olp (7871756), Paul McCusker (634425)   +10 more
core   +1 more source

Transcriptional signatures of somatic neoblasts and germline cells in Macrostomum lignano

eLife, 2016
The regeneration-capable flatworm Macrostomum lignano is a powerful model organism to study the biology of stem cells in vivo. As a flatworm amenable to transgenesis, it complements the historically used planarian flatworm models, such as Schmidtea ...
Magda Grudniewska, Stijn Mouton, Daniil Simanov, Frank Beltman, Margriet Grelling, Katrien de Mulder, Wibowo Arindrarto, Philipp M. Weissert, Stefan van der Elst, Eugene Berezikov   +9 more
doaj   +1 more source

Progress and Challenges in Phylogenomics and Genomics of Lophotrochozoa/Spiralia

Zoologica Scripta, Volume 55, Issue 4, Page 521-544, July 2026.
ABSTRACT Lophotrochozoa is one of the three major bilaterian groups comprising more than half of the bilaterian phyla. Lophotrochozoa includes among others Mollusca, Annelida, Platyhelminthes and Rotifera. Despite representing such a large proportion of animal diversity, they are historically understudied and genomic resources have been scarce. However,
Torsten H. Struck
wiley   +1 more source

The spread of non‐native species

Biological Reviews, Volume 101, Issue 3, Page 1197-1234, June 2026.
ABSTRACT The global redistribution of species through human agency is one of the defining ecological signatures of the Anthropocene, with biological invasions reshaping biodiversity patterns, ecosystem processes and services, and species interactions globally.
Phillip J. Haubrock, Ali Serhan Tarkan, Irene Martín‐Forés, Stelios Katsanevakis, Ronaldo Sousa, Ismael Soto, Andy J. Green, Antonín Kouba, Teun Everts, Victoria Dominguez Almela, Nadège Belouard, Cang Hui, Jamie Bojko, Victor Deklerck, Margaux Boeraeve, Franz Essl, J. Robert Britton   +16 more
wiley   +1 more source

Variation in sex allocation plasticity in three closely related flatworm species [PDF]

, 2019
<p>This dataset accompanies the ' Variation in sex allocation plasticity in three closely related flatworm species ' publication.</p ...
Singh, Pragya (6950522), Nikolas Vellnow, Singh, Pragya, Schärer, Lukas, Pragya Singh, Vellnow, Nikolas, Lukas Schärer, Schärer, Lukas (6950528), Vellnow, Nikolas (6950525)   +8 more
core   +1 more source

Searching for shelter in a ferruginous cave? A new species of Pasipha from a plateau in the Brazilian savanna (Platyhelminthes, Tricladida)

ZooKeys, 2018
In a fauna survey in the eastern margin of Serra do Espinhaço Plateau, in an area belonging to the Brazilian savanna (Cerrado phytophysiognomy), a land flatworm was sampled in a ferruginous cave.
Ana Leal-Zanchet, Alessandro Marques
doaj   +3 more sources

The WORMESH-II flatworm-like mesh robot with 2-DOF double joints

ROBOMECH Journal, 2023
This paper deals with the development of a flatworm-like mesh robot WORMESH-II, which is the second prototype in the WORMESH series inspired from a flattened and soft-bodied flatworm.
Ganegoda V. C. Rasanga, Kengo Hiraishi, Ryuichi Hodoshima, Shinya Kotosaka   +3 more
doaj   +1 more source

ParaHox Genes Revisited: From Gut Patterning to Integrated Axial and Neural Organization in Rotifera

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 4, Page 357-369, June 2026.
In rotifers, ParaHox genes show a dispersed genomic organization, with Xlox absent across gnathiferans. Exclusive neuronal expression of Gsx and Cdx reveals that ancestral ParaHox genes coordinated neural and epithelial development beyond gut patterning, suggesting an integrated role in early bilaterian body plan organization.
Andreas C. Fröbius, David B. Mark Welch, Holger Herlyn   +2 more
wiley   +1 more source

Oases of endemism: Regional aquifer desert springs serve as biodiversity hotspots preserving vulnerable endemic taxa in the Great Basin and Mojave Desert regions

Limnology and Oceanography, Volume 71, Issue 6, June 2026.
Abstract Spring ecosystems in arid regions often serve as crucial biodiversity hotspots by providing some of the only reliable sources of surface water. However, anthropogenic activities and climate change have severely degraded spring ecosystems worldwide, emphasizing the need for large‐scale multidisciplinary studies informing conservation efforts ...
Matthew J. Forrest, Donald W. Sada, Matthew S. Edwards, Robert K. Burton, Richard D. Norris   +4 more
wiley   +1 more source