Results 91 to 100 of about 39,219 (283)

Does a decision support tool designed to depict West Nile virus risk explain variation in ruffed grouse Bonasa umbellus use of managed forests?

open access: yesWildlife Biology, EarlyView.
Infectious diseases are commonly cited as significant contributors to wildlife population declines. It is, therefore, important to investigate the extent to which tools designed to mitigate the effects of infectious diseases explain wildlife responses to habitat management.
Jacob Goldman   +8 more
wiley   +1 more source

Zika Virus: A New Chapter in the History of Medicine

open access: yesActa Médica Portuguesa, 2016
Keywords: Aedes; Arboviruses; Flavivirus; Flaviviridae Infections.
Carlos Brito
doaj   +1 more source

ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cells. [PDF]

open access: yes, 2018
BACKGROUND: Many viruses depend on the extensive membranous network of the endoplasmic reticulum (ER) for their translation, replication, and packaging. Certain membrane modifications of the ER can be a trigger for ER stress, as well as the accumulation ...
Fu, Z   +11 more
core   +1 more source

Maltase 1 regulates DENV2 infection and life history in Aedes aegypti

open access: yesInsect Science, EarlyView.
Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li   +5 more
wiley   +1 more source

Flaviviridae — addition to the family

open access: yesHealth and Ecology Issues, 2019
This review article analyzes and summarizes the history of the replenishment of the family Flaviviridae with new members over the last several decades on the example of the youngest genera of this family - Hepacivirus and Pegivirus .It all started in 1966 when surgeon George Barker, who had hepatitis, had blood serum taken in containing an unknown ...
openaire   +3 more sources

Current Flavivirus Research Important for Vaccine Development

open access: yesVaccines, 2020
The Flaviviridae family of RNA viruses includes numerous human disease-causing pathogens that largely are increasing in prevalence due to continual climate change, rising population sizes and improved ease of global travel [...]
Elizabeth Geerling   +3 more
doaj   +1 more source

Experimental Zika Virus Infection in the Pregnant Common Marmoset Induces Spontaneous Fetal Loss and Neurodevelopmental Abnormalities. [PDF]

open access: yes, 2018
During its most recent outbreak across the Americas, Zika virus (ZIKV) was surprisingly shown to cause fetal loss and congenital malformations in acutely and chronically infected pregnant women.
Aagaard, Kjersti M   +17 more
core   +2 more sources

A Novel Crustavirus as a Candidate Aetiology of Tail Fan Necrosis in New Zealand Red Rock Lobsters, Jasus edwardsii

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Tail fan necrosis (TFN) is a shell disease affecting spiny lobsters' outer integument, with significant implications for the health and commercial viability of red rock lobsters (Jasus edwardsii) in New Zealand. Despite its impact, the potential role of a microbial agent in TFN remains poorly understood.
Rebecca M. Grimwood   +6 more
wiley   +1 more source

Non-primate hepacivirus infection with apparent hepatitis in a horse — Short communication [PDF]

open access: yes, 2014
Non-primate hepacivirus (NPHV) is a recently identified hepacivirus (family Flaviviridae) in dog and horse; however, the disease associations remain unknown.
Boros, Ákos   +3 more
core   +1 more source

Harnessing Viral Proteases for Cellular and Molecular Engineering

open access: yesChemistry–Methods, Volume 5, Issue 9, September 2025.
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui   +2 more
wiley   +1 more source

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