Results 101 to 110 of about 6,094 (193)

Apo B100 similarities to viral proteins suggest basis for LDL-DNA binding and transfection capacity

Journal of Lipid Research, 2010
LDL mediates transfection with plasmid DNA in a variety of cell types in vitro and in several tissues in vivo in the rat. The transfection capacity of LDL is based on apo B100, as arginine/lysine clusters, suggestive of nucleic acid-binding domains and ...
Juan Guevara, Jr., Nagindra Prashad, Boris Ermolinsky, John W. Gaubatz, Dongcheul Kang, Andrea E. Schwarzbach, David S. Loose, Natalia Valentinova Guevara   +7 more
doaj   +1 more source

The Sweet Aspects of Orthoflavivirus Treatment Design and Vaccine Development

Journal of Medical Virology, Volume 97, Issue 10, October 2025.
ABSTRACT Viruses in the genus Orthoflavivirus are among the most important human pathogens because of their significant public health impact. Many strategies have been proposed to develop specific or broad‐spectrum treatments and preventive measures for these viral infections in humans.
Ana C. Alcalá, Michelle Gutiérrez, Juan E. Ludert   +2 more
wiley   +1 more source

Evidências sorológicas da circulação do arbovírus Rocio (Flaviviridae) na Bahia

Revista da Sociedade Brasileira de Medicina Tropical, 1997
Oito casos com anticorpos anti-Rocio são descritos, de quatro cidades do Estado da Bahia, sendo seis portadores de anticorpos IgG (IH e TN) e dois IgM (ELISA e TN).
Andréa Straatmann, Sandro Santos-Torres, Pedro F.C. Vasconcelos, Amélia P.A. Travassos da Rosa, Sueli G. Rodrigues, José Tavares-Neto   +5 more
doaj   +1 more source

Multiple Lineages of Usutu Virus (Flaviviridae, Flavivirus) in Blackbirds (Turdus merula) and Mosquitoes (Culex pipiens, Cx. modestus) in the Czech Republic (2016–2019)

Microorganisms, 2019
Usutu virus (USUV) is a flavivirus (Flaviviridae: Flavivirus) of an African origin transmitted among its natural hosts (diverse species of birds) by mosquitoes.
V. Hönig, Martin Palus, T. Kašpar, Marta Zemanová, Karolina Majerová, L. Hofmannová, P. Papežík, S. Šikutová, F. Rettich, Z. Hubálek, I. Rudolf, J. Votýpka, D. Modrý, D. Růžek   +13 more
semanticscholar   +1 more source

Histopathological Alterations and Dysregulation of Type I Interferon Signaling in the Human Cerebral Cortex During Severe Dengue

Journal of Medical Virology, Volume 97, Issue 10, October 2025.
ABSTRACT Dengue virus (DENV) is a major arthropod‐borne pathogen, endemic in over 100 countries and posing global health challenges. While innate immune responses and viral evasion mechanisms have been extensively studied in animal models and mononuclear cells, severe dengue can affect multiple tissues, including the central nervous system (CNS ...
Leandro Mantovani de Castro, Elaine Raniero Fernandes, Juarez Antonio Simoes Quaresma, Carmen Lucia Penteado Lancelotti, Maria Irma Seixas Duarte, Leda Viegas de Carvalho, Ricardo Penny, Pedro Fernando da Costa Vasconcelos, Evandro Sobroza de Mello, Mirian Nacagami Sotto, Carla Pagliari   +10 more
wiley   +1 more source

Harnessing Viral Proteases for Cellular and Molecular Engineering

Chemistry–Methods, Volume 5, Issue 9, September 2025.
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui, Tien‐Hung Lan, Yubin Zhou   +2 more
wiley   +1 more source

Analysis of Synonymous Codon Usage Bias in Flaviviridae Virus

BioMed Research International, 2019
Background Flaviviridae viruses are single-stranded, positive-sense RNA viruses, which threat human constantly mediated by mosquitoes, ticks, and sandflies.
H. Yao, Mengyu Chen, Zizhong Tang
semanticscholar   +1 more source

A Pyrido‐Quinoxaline Derivative That Downregulates Reticulon 3 Protein Exhibits Potent Antiviral Activity Against Zika Virus

Journal of Medical Virology, Volume 97, Issue 9, September 2025.
ABSTRACT In the wake of the COVID‐19 pandemic, awareness of emerging pathogens has significantly increased, prompting greater investment in research and preparedness. In this context, arboviral diseases are recognized as unmet medical challenges due to their rapid spread. Notably, the geographical range of several flaviviral diseases is expanding: Zika
Erika Plicanti, Andrea Deiana, Silvia Nottoli, Giulia Lottini, Roberta Ibba, Sandra Piras, Carlo Di Marzo, Silvia Vegni, Michele Lai, Mauro Pistello, Antonio Carta, Giulia Freer   +11 more
wiley   +1 more source

New Advances on Zika Virus Research

Viruses, 2019
Zika virus (ZIKV) is an emerging mosquito-borne member of the Flaviviridae family that has historically been known to cause sporadic outbreaks, associated with a mild febrile illness, in Africa and Southeast Asia [...]
Luis Martinez-Sobrido, Fernando Almazán
doaj   +1 more source

Renaming of the genus Flavivirus to Orthoflavivirus and extension of binomial species names within the family Flaviviridae

Archives of Virology, 2023
T. Postler, M. Beer, B. Blitvich, J. Bukh, X. D. de Lamballerie, J. Drexler, A. Imrie, A. Kapoor, G. Karganova, P. Lemey, V. Lohmann, P. Simmonds, Donald B. Smith, J. Stapleton, J. Kuhn   +14 more
semanticscholar   +1 more source