Results 101 to 110 of about 39,219 (283)

G protein-coupled receptor kinase 2 promotes flaviviridae entry and replication. [PDF]

PLoS Neglected Tropical Diseases, 2012
Flaviviruses cause a wide range of severe diseases ranging from encephalitis to hemorrhagic fever. Discovery of host factors that regulate the fate of flaviviruses in infected cells could provide insight into the molecular mechanisms of infection and ...
Caroline Le Sommer, Nicholas J Barrows, Shelton S Bradrick, James L Pearson, Mariano A Garcia-Blanco   +4 more
doaj   +1 more source

Calf pre-weaning traits and immunoglobulin response to bovine viral diarrhea virus vaccination [PDF]

, 2011
Calfhood vaccination for bovine viral diarrhea virus (BVDV) is a relatively new concept, and protocols are evolving. Our objective was to determine effects of BVDV type I vaccination protocol, calf behavior (chute score, and chute exit velocity), and ...
Brown, A. Hayden, Jr., Downum, Whitney, Galloway, Doug B., Hornsby, James A., Johnson, Zelpha B., Kegley, E. Beth, Lindsey, Billy R., Powell, Jermey G.   +7 more
core   +2 more sources

Host Cell Transcriptome Profile during Wild-Type and Attenuated Dengue Virus Infection [PDF]

, 2013
10.1371/journal.pntd.0002107PLoS Neglected Tropical ...
A Becerra, A Sabchareon, A Wilder-Smith, AJ Matlin, AM Nasirudeen, AM Ward, AW Tai, B Malewicz, B Pulendran, BJ Blencowe, C Balas, C Le Sommer, C Trapnell, C Trapnell, CP Simmons, CS Villas-Boas, CY Huang, CY Yu, D Normile, DJ Gubler, DJ Gubler, DS Deluca, DS Shepard, EJ Nascimento, Eng Eong Ooi, ET Wang, Eva Harris, GF Silveira, HA Tissera, HT Long, HY Huang, I Umareddy, J Fink, J Pena, JA Suaya, JC Marioni, JL Kyle, Kenneth C. Goh, KJ Liew, LR Carrasco, LT Hoang, M Le Breton, MD Fernandez-Garcia, ME Beatty, MJ Schreiber, MM Moreno-Altamirano, MN Krishnan, October M. Sessions, OM Sessions, P Loke, Patrick Tan, Q Li, RV Warke, S Ubol, SB Halstead, Steve Rozen, T Tolfvenstam, TM Conceicao, Y Katz, Ying Tan, Yujing Liu, Z Wang   +61 more
core   +4 more sources

Comparative analysis of the extent of protein–protein interactions in icosahedral viral capsids

Protein Science, Volume 34, Issue 9, September 2025.
Abstract Nonenveloped viruses package, carry, and deliver their genomes to the targeted cells using protein shells known as capsids. The viral capsids come in different shapes and sizes, most exhibiting helical or icosahedral symmetries. Here, we analyzed 634 icosahedral capsids at high resolution (<4 Å) from 39 virus families with T‐numbers ranging ...
Noah J. Zimmerman, Oscar Rojas Labra, Vijay S. Reddy   +2 more
wiley   +1 more source

Identification and molecular characterization of highly divergent RNA viruses in cattle, Uganda.

Virus Research, 2022
The risk for the emergence of novel viral zoonotic diseases in animals and humans in Uganda is high given its geographical location with high biodiversity.
Stephen Balinandi, Juliette Hayer, Harindranath Cholleti, Michelle Wille, Julius J. Lutwama, Maja Malmberg, Lawrence Mugisha   +6 more
doaj   +1 more source

The Small Cysteine‐Rich Protein of Potato Mop‐Top Virus Exhibits Viroporin Activity

Molecular Plant Pathology, Volume 26, Issue 9, September 2025.
The cysteine‐rich 8K protein of PMTV exhibits a viroporin activity that forms multimers on endomembrane, alters membrane permeability, and conducts potassium and protons. ABSTRACT Potato mop‐top virus (PMTV) is the causal agent of potato tuber spraing disease, which causes significant economic losses to potato production worldwide.
Ye Liu, Xinyue Fan, Yameng Luan, Yong Li, Yu Zhao, Weiqin Ji, Naihui Li, Xiaoyun Wu, Xiaofei Cheng, Yanju Bai   +9 more
wiley   +1 more source

Initiation of hepatitis C virus infection is dependent on cholesterol and cooperativity between CD81 and scavenger receptor B type I. [PDF]

, 2006
In the past several years, a number of cellular proteins have been identified as candidate entry receptors for hepatitis C virus (HCV) by using surrogate models of HCV infection.
Barth, Heidi, Baumert, Thomas, Chisari, Francis V, Kapadia, Sharookh B, McKeating, Jane A   +4 more
core   +2 more sources

Phosphatidylethanolamine: A key player in lung disease

Clinical and Translational Discovery, Volume 5, Issue 4, August 2025.
Implication of PE in the aetiology of diverse diseases. The pivotal role of PE in driving lipid peroxidation during ferroptosis. Implications of PE metabolic dysregulation in pulmonary epithelial cells. Abstract Phosphatidylethanolamine (PE) is a pivotal glycerophospholipid that constitutes a significant portion of cellular membranes, playing a crucial
Linlin Zhang, Wanxin Duan, Liyang Li
wiley   +1 more source

Space constrained homology modelling: The paradigm of the RNA-dependent RNA polymerase of dengue (Type II) virus [PDF]

, 2013
Protein structure is more conserved than sequence in nature. In this direction we developed a novel methodology that significantly improves conventional homology modelling when sequence identity is low, by taking into consideration 3D structural features
Kontopoulos, DG, Kossida, S, Vlachakis, D   +2 more
core   +2 more sources

Human T Cell Responses to Flavivirus Vaccines

European Journal of Immunology, Volume 55, Issue 8, August 2025.
This review summarises current knowledge of T cell responses induced by flavivirus vaccines being licensed or under development. Existing vaccines against flaviviruses have been developed and analysed primarily in the context of antibody responses, while the role of T cells in contributing to immunity against flaviviruses is less studied.
David Wullimann, Hans‐Gustaf Ljunggren
wiley   +1 more source