Results 111 to 120 of about 6,094 (193)
Japanese Encephalitis Virus Genotype 5 Infectious Clone and Reporter System for Antiviral Evaluation
Journal of Medical Virology, Volume 97, Issue 9, September 2025.ABSTRACT The recent emergence of Japanese encephalitis virus genotype 5 (JEV5) has raised concerns regarding limited vaccine efficacy. Here, we report the construction of a full‐length infectious cDNA clone of JEV5 using a bacterial artificial chromosome (BAC) system, based on a South Korea isolate, K15P38 strain.
Jae‐Yeon Park +3 more
wiley +1 more source
Comparative analysis of the extent of protein–protein interactions in icosahedral viral capsids
Protein Science, Volume 34, Issue 9, September 2025.Abstract Nonenveloped viruses package, carry, and deliver their genomes to the targeted cells using protein shells known as capsids. The viral capsids come in different shapes and sizes, most exhibiting helical or icosahedral symmetries. Here, we analyzed 634 icosahedral capsids at high resolution (<4 Å) from 39 virus families with T‐numbers ranging ...
Noah J. Zimmerman +2 more
wiley +1 more source
RNA chaperoning and intrinsic disorder in the core proteins of Flaviviridae
Nucleic Acids Research, 2007 RNA chaperone proteins are essential partners of RNA in living organisms and viruses. They are thought to assist in the correct folding and structural rearrangements of RNA molecules by resolving misfolded RNA species in an ATP-independent manner. RNA chaperoning is probably an entropy-driven process, mediated by the coupled binding and folding of ...
Ivanyi-Nagy, R. +4 more
openaire +4 more sources
The Small Cysteine‐Rich Protein of Potato Mop‐Top Virus Exhibits Viroporin Activity
Molecular Plant Pathology, Volume 26, Issue 9, September 2025.The cysteine‐rich 8K protein of PMTV exhibits a viroporin activity that forms multimers on endomembrane, alters membrane permeability, and conducts potassium and protons. ABSTRACT Potato mop‐top virus (PMTV) is the causal agent of potato tuber spraing disease, which causes significant economic losses to potato production worldwide.
Ye Liu +9 more
wiley +1 more source
Viruses, 2019 Prevalence studies have demonstrated a global distribution of equine hepacivirus (EqHV), a member of the family Flaviviridae. However, apart from a single case of vertical transmission, natural routes of EqHV transmission remain elusive.
Marcha Badenhorst +8 more
semanticscholar +1 more source
Broad-spectrum inhibitor of viruses in the Flaviviridae family
Antiviral Research, 2005 The viruses in the Flaviviridae family have been associated with human and animal diseases. In this report, we demonstrate that compound 2-amino-8-(beta-D-ribofuranosyl) imidazo [1,2-a]-s-triazine-4-one (ZX-2401) was capable of inhibiting the production in culture of at least five members of the Flaviviridae family with minimal cytotoxicity.
Ojwang, J. O. +5 more
openaire +3 more sources
Non-Canonical Roles of Dengue Virus Non-Structural Proteins
Viruses, 2017 The Flaviviridae family comprises a number of human pathogens, which, although sharing structural and functional features, cause diseases with very different outcomes.
Julianna D. Zeidler +3 more
doaj +1 more source
Emerging Role of l-Dopa Decarboxylase in Flaviviridae Virus Infections
Cells, 2019 l-dopa decarboxylase (DDC) that catalyzes the biosynthesis of bioactive amines, such as dopamine and serotonin, is expressed in the nervous system and peripheral tissues, including the liver, where its physiological role remains unknown.
E. Frakolaki +8 more
semanticscholar +1 more source
Use of Flaviviral genetic fragments as a potential prevention strategy for HIV-1 Silencing
Journal of Infection in Developing Countries, 2016 Introduction: Coinfection with certain members of the Flaviviridae, such as Dengue Virus (DV), West Nile Virus (WNV) Yellow Fever Virus (YFV) and most importantly, GBV-C have been documented to reduce HIV-1 viral load in vivo.
Muhammad Sheraz +9 more
doaj +1 more source
Genomic organization of GB viruses A and B: two new members of the Flaviviridae associated with GB agent hepatitis [PDF]
, 1995 A. Scott Muerhoff +9 more
openalex +1 more source