Results 121 to 130 of about 39,219 (283)

Regulation of positive-strand RNA virus replication: The emerging role of phosphorylation. [PDF]

open access: yes, 2007
Protein phosphorylation is a reversible post-translational modification that plays a fundamental role in the regulation of many cellular processes.
Jakubiec, Anna, Jupin, Isabelle
core   +3 more sources

The Antiviral Activity of Polyphenols

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard   +5 more
wiley   +1 more source

Evidências sorológicas da circulação do arbovírus Rocio (Flaviviridae) na Bahia

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 1997
Oito casos com anticorpos anti-Rocio são descritos, de quatro cidades do Estado da Bahia, sendo seis portadores de anticorpos IgG (IH e TN) e dois IgM (ELISA e TN).
Andréa Straatmann   +5 more
doaj   +1 more source

Hepatitis C virus relies on lipoproteins for its life cycle [PDF]

open access: yes, 2016
Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and hepatocellular carcinoma.
Alonzi, Tonino   +5 more
core   +1 more source

West Nile Virus positivity amongst Canadian blood donors and effectiveness of off‐season screening

open access: yesTransfusion, Volume 65, Issue 8, Page 1484-1489, August 2025.
Abstract Background We sought to examine the prevalence of West Nile Virus (WNV) nucleic acid test (NAT) positivity over time in Canadian blood donors, examine the level of false‐positive NAT screening, and understand the effectiveness of travel‐related testing outside of WNV seasonality in Canada. Study Design and Methods All blood donations in Canada
Carmen L. Charlton   +8 more
wiley   +1 more source

Zika virus:a previously slow pandemic spreads rapidly through the Americas [PDF]

open access: yes, 2016
Zika virus (Flaviviridae) is an emerging arbovirus. Spread by Aedes mosquitoes, it was first discovered in Uganda in 1947, and later in humans elsewhere in sub-Saharan Africa, arriving in south-east Asia at latest by mid-20th-century. In the 21st century,
Gatherer, Derek, Kohl, Alain
core   +2 more sources

Analysis of Synonymous Codon Usage Bias in Flaviviridae Virus

open access: yesBioMed Research International, 2019
Background Flaviviridae viruses are single-stranded, positive-sense RNA viruses, which threat human constantly mediated by mosquitoes, ticks, and sandflies.
H. Yao, Mengyu Chen, Zizhong Tang
semanticscholar   +1 more source

Insights into the Dynamics and Binding Mechanisms of the Alkhumra Virus NS2B/NS3 Protease: A Molecular Dynamics Study

open access: yesAdvanced Theory and Simulations, Volume 8, Issue 7, July 2025.
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak   +2 more
wiley   +1 more source

New Advances on Zika Virus Research

open access: yesViruses, 2019
Zika virus (ZIKV) is an emerging mosquito-borne member of the Flaviviridae family that has historically been known to cause sporadic outbreaks, associated with a mild febrile illness, in Africa and Southeast Asia [...]
Luis Martinez-Sobrido, Fernando Almazán
doaj   +1 more source

DDX3 Regulates the Cap‐Independent Translation of the Japanese Encephalitis Virus via Its Interactions with PABP1 and the Untranslated Regions of the Viral Genome

open access: yesAdvanced Science, Volume 12, Issue 27, July 17, 2025.
Japanese encephalitis virus (JEV) employs a cap‐independent (CI) translation strategy to evade host translational shutoff. During the shut‐off of host cellular canonical translation, DEAD‐box protein 3 (DDX3) bind to JEV UTRs to establish a closed‐loop architecture, and its interaction with poly(A)‐binding protein 1 (PABP1) to form DDX3/PABP1/eIF4G ...
Chenxi Li   +13 more
wiley   +1 more source

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