Results 121 to 130 of about 39,219 (283)
Regulation of positive-strand RNA virus replication: The emerging role of phosphorylation. [PDF]
Protein phosphorylation is a reversible post-translational modification that plays a fundamental role in the regulation of many cellular processes.
Jakubiec, Anna, Jupin, Isabelle
core +3 more sources
The Antiviral Activity of Polyphenols
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard+5 more
wiley +1 more source
Evidências sorológicas da circulação do arbovírus Rocio (Flaviviridae) na Bahia
Oito casos com anticorpos anti-Rocio são descritos, de quatro cidades do Estado da Bahia, sendo seis portadores de anticorpos IgG (IH e TN) e dois IgM (ELISA e TN).
Andréa Straatmann+5 more
doaj +1 more source
Hepatitis C virus relies on lipoproteins for its life cycle [PDF]
Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and hepatocellular carcinoma.
Alonzi, Tonino+5 more
core +1 more source
West Nile Virus positivity amongst Canadian blood donors and effectiveness of off‐season screening
Abstract Background We sought to examine the prevalence of West Nile Virus (WNV) nucleic acid test (NAT) positivity over time in Canadian blood donors, examine the level of false‐positive NAT screening, and understand the effectiveness of travel‐related testing outside of WNV seasonality in Canada. Study Design and Methods All blood donations in Canada
Carmen L. Charlton+8 more
wiley +1 more source
Zika virus:a previously slow pandemic spreads rapidly through the Americas [PDF]
Zika virus (Flaviviridae) is an emerging arbovirus. Spread by Aedes mosquitoes, it was first discovered in Uganda in 1947, and later in humans elsewhere in sub-Saharan Africa, arriving in south-east Asia at latest by mid-20th-century. In the 21st century,
Gatherer, Derek, Kohl, Alain
core +2 more sources
Analysis of Synonymous Codon Usage Bias in Flaviviridae Virus
Background Flaviviridae viruses are single-stranded, positive-sense RNA viruses, which threat human constantly mediated by mosquitoes, ticks, and sandflies.
H. Yao, Mengyu Chen, Zizhong Tang
semanticscholar +1 more source
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak+2 more
wiley +1 more source
New Advances on Zika Virus Research
Zika virus (ZIKV) is an emerging mosquito-borne member of the Flaviviridae family that has historically been known to cause sporadic outbreaks, associated with a mild febrile illness, in Africa and Southeast Asia [...]
Luis Martinez-Sobrido, Fernando Almazán
doaj +1 more source
Japanese encephalitis virus (JEV) employs a cap‐independent (CI) translation strategy to evade host translational shutoff. During the shut‐off of host cellular canonical translation, DEAD‐box protein 3 (DDX3) bind to JEV UTRs to establish a closed‐loop architecture, and its interaction with poly(A)‐binding protein 1 (PABP1) to form DDX3/PABP1/eIF4G ...
Chenxi Li+13 more
wiley +1 more source