Results 241 to 250 of about 39,219 (283)

Complete coding sequence of goose-derived cluster 3.2 Tembusu virus from Anhui province of China in October 2024. [PDF]

Microbiol Resour Announc
Zhao L, Zhu J, He S-J, Ye P-F, Kong J, Zhang L-J.   +5 more
europepmc   +1 more source

N6 -Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection

Cell Host and Microbe, 2016
Nandan Satish Gokhale, Alexa B R Mcintyre, Michael J Mcfadden   +2 more
exaly   +2 more sources

Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens

Nature, 2016
The Flaviviridae are a family of viruses that cause severe human diseases. For example, dengue virus (DENV) is a rapidly emerging pathogen causing an estimated 100 million symptomatic infections annually worldwide. No approved antivirals are available to
Andreas S Puschnik, Karim Majzoub, Yaw Shin Ooi   +2 more
exaly   +2 more sources

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Pseudotyped Virus for Flaviviridae

2023
Members of Flaviviridae are enveloped single positive-stranded RNA viruses including hepacivirus, pestivirus, pegivirus, and mosquito-transmitted flavivirus, which are important pathogens of infectious diseases and pose serious threats to human health.
Leiliang, Zhang, Xiao, Wang, Annan, Ming, Wenjie, Tan   +3 more
openaire   +2 more sources

Zika Virus Genomic RNA Possesses Conserved G-Quadruplexes Characteristic of the Flaviviridae Family

ACS Infectious Diseases, 2016
Zika virus has emerged as a global concern because neither a vaccine nor antiviral compounds targeting it exist. A structure for the positive-sense RNA genome has not been established, leading us to look for potential G-quadruplex sequences (PQS) in the ...
Aaron M Fleming, Yun Ding, Anton Alenko
exaly   +2 more sources

[Flaviviridae and mitochondria: Everything you always wanted to know about their relationship but were afraid to ask].

Virologie, 2021
Infections with Flaviviridae constitute a major public health concern, especially considering the limited availability of prophylactic and therapeutic treatments.
Wesley Freppel, M. Roy, Laurent Chatel-Chaix   +2 more
semanticscholar   +1 more source

Replicative/transcription enzymes of Flaviviridae.

Virologie (Montrouge, France), 2013
The family Flaviviridae comprises several major human pathogens including Hepatitis C virus (genus hepacivirus), yellow fever virus or dengue virus (genus flavivirus). The Flaviviridae genomes are made of a single stranded RNA segment that encodes seven non-structural proteins : NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5 in the flaviviruses like dengue ...
Bressanelli, Stéphane, Lescar, Julien
openaire   +5 more sources

The hepatic flaviviridae: summary

Journal of Viral Hepatitis, 1999
Hepatitis C envelope proteins (E1, E2) induce protective neutralizing antibodies. The extent of sequence diversity reflects the host's ability to control viral populations and the response to antiviral therapy. Attempts to prepare effective vaccines against HCV are foiled by lack of prolonged protective immunity.
openaire   +3 more sources

Flaviviridae polymerase and RNA replication

Journal of Viral Hepatitis, 1999
Sequence motifs within the non‐structural protein NS5 or NS5B of the members of the family Flaviviridae suggest that this protein is the RNA‐dependent RNA polymerase. This protein has now been expressed in various in vitro systems and used in polymerase assays.
P. Thompson, A. Bartholomeusz
openaire   +3 more sources

Defective adenoviruses as novel vaccines for the Flaviviridae

Clinical and Diagnostic Virology, 1998
Vaccines against many flaviviruses, such as Japanese encephalitis virus (JEV), yellow fever virus (YFV) and tick-borne encephalitis virus (TBEV), have been successfully used for many years. Other diseases such as dengue fever (DF) and hepatitis C are still major public health problems as no licensed vaccines are in use.To review studies on the use of ...
openaire   +3 more sources