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Flavivirus: From Structure to Therapeutics Development
Life, 2021 Flaviviruses are still a hidden threat to global human safety, as we are reminded by recent reports of dengue virus infections in Singapore and African-lineage-like Zika virus infections in Brazil.
Rong Zhao +6 more
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Flavivirus NS1 and Its Potential in Vaccine Development
Vaccines, 2021 The Flavivirus genus contains many important human pathogens, including dengue, Japanese encephalitis (JE), tick-borne encephalitis (TBE), West Nile (WN), yellow fever (YF) and Zika (ZIK) viruses.
Kassandra L. Carpio, Alan D. T. Barrett
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A Perspective on Current Flavivirus Vaccine Development: A Brief Review
Viruses, 2023 The flavivirus genus contains several clinically important pathogens that account for tremendous global suffering. Primarily transmitted by mosquitos or ticks, these viruses can cause severe and potentially fatal diseases ranging from hemorrhagic fevers ...
Sudip Kumar Dutta, Thomas Langenburg
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Viruses, 2021 Flaviviruses are known to cause a variety of diseases in humans in different parts of the world. There are very limited numbers of antivirals to combat flavivirus infection, and therefore new drug targets must be explored.
Abdul Wahaab +8 more
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Serological Diagnosis of Flavivirus-Associated Human Infections
Diagnostics, 2020 Arthropod-borne viruses (arboviruses) belonging to the Flavivirus genus of the Flaviviridae family, are a major public health threat in tropical and subtropical regions, and have recently become a medical concern in temperate zones. Most flaviviruses are
Didier Musso, Philippe Desprès
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Phenotypic and Genetic Variability of Isolates of ZIKV-2016 in Brazil
Microorganisms, 2022 The possibility of a Zika virus epidemic resurgence requires studies to understand its mechanisms of pathogenicity. Here, we describe the isolation of the Zika virus from breast milk (Rio-BM1) and compare its genetic and virological properties with two ...
Lidiane Menezes Souza Raphael +11 more
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Chikungunya Virus Shedding in Semen: A Case Series
Viruses, 2022 Background: Chikungunya is a viral disease that is transmitted by mosquitoes. It is characterized by an acute onset of fever and severe arthralgia. Methods: We describe six cases of acute and post-acute chikungunya in which viral RNA was detected in ...
Ezequias B. Martins +16 more
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Structural basis for antibody inhibition of flavivirus NS1–triggered endothelial dysfunction
Science, 2021 Two antibodies against flaviviruses Flaviviruses are a group of RNA viruses that include the human pathogens dengue virus, Zika virus, and West Nile virus.
Scott B. Biering +19 more
semanticscholar +1 more source
Evolution and activation mechanism of the flavivirus class II membrane-fusion machinery
Nature Communications, 2022 The flavivirus envelope glycoproteins prM and E drive the assembly of icosahedral, spiky immature particles that bud across the membrane of the endoplasmic reticulum.
M. Vaney +9 more
semanticscholar +1 more source
Implementación de un sistema de detección de flavivirus en mosquitos
Memorias del Instituto de Investigaciones en Ciencias de la Salud, 2021 Los Flavivirus constituyen virus transmitidos por artrópodos, principalmente mosquitos. Pueden producir enfermedades en humanos y animales, también incluyen virus específicos de insectos que solo infectan y se replican en los insectos, no así en ...
Fátima Cardozo +8 more
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