Evaluating the specificity of flavivirus proteases in Aedes aegypti cells for dengue virus 2-derived cleavage sites. [PDF]
Flaviviruses are a diverse group of RNA viruses known for their significant impact on human health worldwide. We generated a series of reporters that included cleavage sequences from the dengue virus type 2 polyprotein and co-transfected with plasmids ...
Alexius O Dingle, Zach N Adelman
doaj +2 more sources
Phenotypic and Genetic Variability of Isolates of ZIKV-2016 in Brazil
The possibility of a Zika virus epidemic resurgence requires studies to understand its mechanisms of pathogenicity. Here, we describe the isolation of the Zika virus from breast milk (Rio-BM1) and compare its genetic and virological properties with two ...
Lidiane Menezes Souza Raphael+11 more
doaj +1 more source
Chikungunya Virus Shedding in Semen: A Case Series
Background: Chikungunya is a viral disease that is transmitted by mosquitoes. It is characterized by an acute onset of fever and severe arthralgia. Methods: We describe six cases of acute and post-acute chikungunya in which viral RNA was detected in ...
Ezequias B. Martins+16 more
doaj +1 more source
Implementación de un sistema de detección de flavivirus en mosquitos
Los Flavivirus constituyen virus transmitidos por artrópodos, principalmente mosquitos. Pueden producir enfermedades en humanos y animales, también incluyen virus específicos de insectos que solo infectan y se replican en los insectos, no así en ...
Fátima Cardozo+8 more
doaj +1 more source
The Chikungunya virus infection in Brazil has raised several concerns due to the rapid dissemination of the virus and its association with several clinical complications.
Allison Araújo Fabri+13 more
doaj +1 more source
Recombinant Envelope-Proteins with Mutations in the Conserved Fusion Loop Allow Specific Serological Diagnosis of Dengue-Infections [PDF]
Dengue virus (DENV) is a mosquito-borne flavivirus and a major international public health concern in many tropical and sub-tropical areas worldwide. DENV is divided into four major serotypes, and infection with one serotype leads to immunity against the
Barzon, Luisa+5 more
core +7 more sources
Flavivirus Concentrates Host ER in Main Replication Compartments to Facilitate Replication
Flavivirus remodels the host endoplasmic reticulum (ER) to generate replication compartments (RCs) as the fundamental structures to accommodate viral replication.
Yali Ci+6 more
doaj +1 more source
Serological evidence for Japanese encephalitis and West Nile virus infections in domestic birds in Cambodia [PDF]
Mosquito-borne flaviviruses with an enzootic transmission cycle like Japanese encephalitis virus (JEV) and West Nile virus (WNV) are a major public health concern.
Auerswald, Heidi+10 more
core +2 more sources
A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis [PDF]
The structural flexibility or 'breathing' of the envelope (E) protein of flaviviruses allows virions to sample an ensemble of conformations at equilibrium.
Diamond, Michael S+4 more
core +10 more sources
Classical insect-flaviviruses (cISFVs) and dual host-related insect-specific flavivirus (dISFV) are within the major group of insect-specific flavivirus.
Geovani de Oliveira Ribeiro+23 more
doaj +1 more source