Results 1 to 10 of about 59,356 (219)

The Zika outbreak of the 21st century. [PDF]

open access: yes, 2016
The Zika virus outbreak has captivated the attention of the global audience and information has spread rapidly and wildly through the internet and other media channels.
Ansari, Aftab   +3 more
core   +1 more source

Detection of a new insect flavivirus and isolation of Aedes flavivirus in Northern Italy

open access: yesParasites & Vectors, 2012
Background During recent years, numerous novel ‘insect flaviviruses’ have been discovered in natural mosquito populations. In a previous study we described the presence of flavivirus DNA sequences integrated in Aedes albopictus (Asian tiger mosquito ...
Roiz David   +9 more
doaj   +1 more source

A targeted approach with nanopore sequencing for the universal detection and identification of flaviviruses

open access: yesScientific Reports, 2021
Nucleic acid test (NAT), most typically quantitative PCR, is one of the standard methods for species specific flavivirus diagnosis. Semi-comprehensive NATs such as pan-flavivirus PCR which covers genus Flavivirus are also available; however, further ...
Patrick Reteng   +12 more
doaj   +1 more source

Potential Role of Flavivirus NS2B-NS3 Proteases in Viral Pathogenesis and Anti-flavivirus Drug Discovery Employing Animal Cells and Models: A Review

open access: yesViruses, 2021
Flaviviruses are known to cause a variety of diseases in humans in different parts of the world. There are very limited numbers of antivirals to combat flavivirus infection, and therefore new drug targets must be explored.
Abdul Wahaab   +8 more
doaj   +1 more source

Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus [PDF]

open access: yes, 2011
We provide experimental evidence of a replication enhancer element (REE) within the capsid gene of tick-borne encephalitis virus (TBEV, genus Flavivirus).
Buckley, A.   +5 more
core   +3 more sources

Neutropenia as an adverse event following vaccination : results from randomized clinical trials in healthy adults and systematic review [PDF]

open access: yes, 2016
Background : In the context of early vaccine trials aimed at evaluating the safety profile of novel vaccines, abnormal haematological values, such as neutropenia, are often reported.
Aerssens, Annelies   +10 more
core   +8 more sources

Chimeric Yellow Fever/Dengue Virus as a Candidate Dengue Vaccine: Quantitation of the Dengue Virus-Specific CD8 T-Cell Response [PDF]

open access: yes, 2000
We have constructed a chimeric yellow fever/dengue (YF/DEN) virus, which expresses the premembrane (prM) and envelope (E) genes from DEN type 2 (DEN-2) virus in a YF virus (YFV-17D) genetic background. Immunization of BALB/c mice with this chimeric virus
Ahmed, Rafi   +3 more
core   +2 more sources

Characterization of Zika virus endocytic pathways in human glioblastoma cells [PDF]

open access: yes, 2020
Zika virus (ZIKV) infections can cause microcephaly and neurological disorders. However, the early infection events of ZIKV in neural cells remain to be characterized. Here, by using a combination of pharmacological and molecular approaches and the human
Du, T   +11 more
core   +1 more source

First detection and molecular characterization of a DENV‐1/DENV‐4 co‐infection during an epidemic in Rio de Janeiro, Brazil

open access: yesClinical Case Reports, 2018
Key Clinical Message In the 80s, dengue viruses type 1 and 4 (DENV‐1 and 4) were isolated in North region of Brazil. However, it was only after the DENV‐1 introduction in the state of Rio de Janeiro (RJ) in mid‐1980s, that dengue became a nationwide ...
Fernanda de Bruycker‐Nogueira   +5 more
doaj   +1 more source

Resveratrol as an epigenetic therapy for flavivirus infection: A narrative review

open access: yesAsian Pacific Journal of Tropical Medicine, 2023
Flaviviruses are a group of positive-stranded RNA viruses that cause a broad spectrum of severe illnesses in humans worldwide. Clinical manifestations of flavivirus infections range from mild febrile illness to hemorrhage, shock, and neurological ...
Kim-Ling Chin   +3 more
doaj   +1 more source

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