Results 101 to 110 of about 60,474 (247)

Carbon Quantum Dots Assisted Virus Tracking: From Skin to Brain

Advanced Materials, Volume 38, Issue 6, 27 January 2026.
A novel carbon quantum dots‐dissolvable microneedle, CQDs‐dMN system, enables painless delivery and real‐time tracking of HSV‐1. The HSV‐1 is labeled with fluorescent CQDs and delivered to the skin dermis, minimizing damage compared to traditional methods.
Yaxiu Feng, Xiong Wang, Cien Chen, Di Wang, Changshun Hou, Yiran Wang, Huan Hu, Peiran Chen, LeiYing Qin, Qianya Wan, Xi Yao, Ming‐Liang He   +11 more
wiley   +1 more source

Membrane and envelope virus proteins co-expressed as lysosome associated membrane protein (LAMP) fused antigens: a potential tool to develop DNA vaccines against flaviviruses

Anais da Academia Brasileira de Ciências, 2009
Vaccination is the most practical and cost-effective strategy to prevent the majority of the flavivirus infection to which there is an available vaccine. However, vaccines based on attenuated virus can potentially promote collateral side effects and even
Rafael Dhalia, Milton Maciel Jr., Fábia S.P. Cruz, Isabelle F.T. Viana, Mariana L. Palma, Thomas August, Ernesto T.A. Marques Jr.   +6 more
doaj   +1 more source

A 212-nt long RNA structure in the Tobacco necrosis virus-D RNA genome is resistant to Xrn degradation [PDF]

, 2019
Plus-strand RNA viruses can accumulate viral RNA degradation products during infections. Some of these decay intermediates are generated by the cytosolic 5′-to-3′ exoribonuclease Xrn1 (mammals and yeast) or Xrn4 (plants) and are formed when the enzyme ...
Chaminda, Gunawardene D., Newburn, Laura R., White, K. Andrew   +2 more
core   +1 more source

Universal Regulation of DNA Polymerase via Photocaged Primer Enables Light‐Start Isothermal Amplification on Demand

Advanced Science, Volume 13, Issue 3, 14 January 2026.
A simple and general photoactivatable approach is developed to regulate DNA polymerase activity, enabling light‐start isothermal amplification on demand. The molecular dynamics simulations reveals that the photocaged primer blocks DNA polymerase activity by inhibiting the conformational change of the polymerase.
Min Qing, Yufan Qin, Zhijin Li, Xiufang Yu, Jianbo Wang, Xiaoqiong Liu, Xin Chen, Chao Yu   +7 more
wiley   +1 more source

The glycosylation deficiency of flavivirus NS1 attenuates virus replication through interfering with the formation of viral replication compartments

Journal of Biomedical Science
Background Flavivirus is a challenge all over the world. The replication of flavivirus takes place within membranous replication compartments (RCs) derived from endoplasmic reticulum (ER).
Shuhan Huang, Pan-Deng Shi, Xiao-Xuan Fan, Yang Yang, Cheng-Feng Qin, Hui Zhao, Lei Shi, Yali Ci   +7 more
doaj   +1 more source

Crystal structure of the NS3-like helicase from Alongshan virus

IUCrJ, 2020
Alongshan virus (ALSV) is an emerging human pathogen that was identified in China and rapidly spread to the European continent in 2019, raising concerns about public health.
Xiaopan Gao, Kaixiang Zhu, Justyna Aleksandra Wojdyla, Pu Chen, Bo Qin, Ziheng Li, Meitian Wang, Sheng Cui   +7 more
doaj   +1 more source

Insect I‐Type Lysozymes Function as Antiviral Proteases by Forming Biomolecular Condensates

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Upon rice viral infection, the insect vector activates the Toll–MyD88–Dorsal signaling cascade, inducing i‐type lysozyme (Lyz‐I1) expression. Lyz‐I1 functions as an antiviral protease through its conserved catalytic dyad Glu/Asp (E/D), mediating cleavage of viral proteins at specific Lys (K) residues.
Yu Du, Yuqing Xiao, Manman Hu, Jinhua Yang, You Li, Taiyun Wei   +5 more
wiley   +1 more source

Prevalence of Flavivirus and Alphavirus in bats captured in the state of Yucatan, southeastern Mexico

One Health
Summary: Flavivirus (family Flaviviridae) and Alphavirus (family Togaviridae) are mosquito-borne viruses that poses a significant risk to public health worldwide.
Aaron Yeh-Gorocica, Marco Torres-Castro, Claudia Carrillo-Chan, Alejandro Suarez-Galaz, Melissa Suarez-Galaz, Wilson Moguel-Chin, Alonso Panti-May, Cesar Lugo-Caballero, Henry Puerta-Guardo, Juan Chable-Santos, Pablo Manrique-Saide, Guadalupe Ayora-Talavera, Celia Selem-Salas, Mario Frias-Casas, Antonio Rivero-Juarez   +14 more
doaj   +1 more source

Wolbachia and arbovirus inhibition in mosquitoes [PDF]

, 2013
Wolbachia is a maternally inherited intracellular bacteria that can manipulate the reproduction of their insect hosts, and cytoplasmic incompatibility allows them to spread through mosquito populations.
Sinkins, Steven P.
core   +1 more source

Aptamer‐Engineered Ellipsometry for Clinical Detection of BALF‐Derived Exosomes: Multi‐Level Engineering for Prognostic Evaluation of Immunotherapy Responses

Advanced Science, Volume 13, Issue 3, 14 January 2026.
A novel ellipsometry platform functionalized with truncated PD‐L1 aptamers are developed to enable ultrasensitive detection of BALF‐derived exosomes. Through chemical ligand tailoring, mechanical sensing optimization, and tumor‐proximal fluid sampling, the system precisely stratifies ICI responders and non‐responders, offering superior sensitivity and ...
Euna Jeong, Jung Hyun Choi, Minyoung Lee, Jun Hyeok Lim, Seokho Jung, Yeeun Woo, Joo‐young Kim, Jaehyeon Ok, Lucia Kim, Woo‐jin Jeong, Won Chegal, Hyun Mo Cho, Chulhwan Park, Jiyoon Bu, Dong Hyung Kim, Taek Lee   +15 more
wiley   +1 more source