Results 21 to 30 of about 45,475 (259)
Astrocytes in Flavivirus Infections [PDF]
Virus infections of the central nervous system (CNS) can manifest in various forms of inflammation, including that of the brain (encephalitis) and spinal cord (myelitis), all of which may have long-lasting deleterious consequences. Although the knowledge of how different viruses affect neural cells is increasing, understanding of the mechanisms by ...
Maja Potokar+2 more
openaire +4 more sources
Insect‐specific viruses used in biocontrol of mosquito‐borne diseases
Insect‐specific RNA viruses (ISRVs) are involved in a wide range of families including Flaviviridae, Bunyaviridae, Negeviruses, Togaviridae, Reoviridae, Mesoniviridae, and Rhabdoviridae, which cannot infect vertebrates, including humans. However, ISRVs can infect and replicate in mosquitoes, interfering with the replication of mosquito‐borne viruses ...
Jiating Chen+2 more
wiley +1 more source
Flavivirus Concentrates Host ER in Main Replication Compartments to Facilitate Replication
Flavivirus remodels the host endoplasmic reticulum (ER) to generate replication compartments (RCs) as the fundamental structures to accommodate viral replication.
Yali Ci+6 more
doaj +1 more source
Pathogenesis and virulence of flavivirus infections [PDF]
The Flavivirus genus consists of >70 members including several that are considered significant human pathogens. Flaviviruses display a broad spectrum of diseases that can be roughly categorised into two phenotypes - systemic disease involving haemorrhage exemplified by dengue and yellow Fever virus, and neurological complications associated with the ...
van Leur, SW+3 more
openaire +3 more sources
A little less aggregation a little more replication: Viral manipulation of stress granules
Viruses depend entirely on host machinery and therefore aim to conquer the host and defeat its defenses to co‐opt its resources for its own replication. Improved understanding of how viruses counteract host immune responses such as stress granule assembly, detailed here, will inform future antiviral therapeutic strategies.
Matthew J. Brownsword, Nicolas Locker
wiley +1 more source
Hepatitis B virus movement through the hepatocyte: An update
Model of intracellular trafficking routes of progeny hepatitis B virus (HBV) viral and subviral particles through the liver cell involving nucleocytoplasmic shuttling, movement through the ER/Golgi secretory pathway, and budding and release through the multivesicular body (MVB) and/or secretory autophagosomes (sAP) axis.
Reinhild Prange
wiley +1 more source
Serological evidence for Japanese encephalitis and West Nile virus infections in domestic birds in Cambodia [PDF]
Mosquito-borne flaviviruses with an enzootic transmission cycle like Japanese encephalitis virus (JEV) and West Nile virus (WNV) are a major public health concern.
Auerswald, Heidi+10 more
core +1 more source
Flavivirus: From Structure to Therapeutics Development
Flaviviruses are still a hidden threat to global human safety, as we are reminded by recent reports of dengue virus infections in Singapore and African-lineage-like Zika virus infections in Brazil.
Rong Zhao+6 more
doaj +1 more source
Abstract Malaria is a mosquito‐borne disease caused by protozoans of the genus Plasmodium that affects both humans and wildlife. The fitness consequences of infections by avian malaria are well known in birds, however, little information exists on its impact on mosquitoes.
Marta Garrigós+4 more
wiley +1 more source
Memory T Cells in Flavivirus Vaccination [PDF]
Flaviviruses include many medically important viruses, such as Dengue virus (DENV), Japanese encephalitis (JEV), tick-borne encephalitis (TBEV), West Nile (WNV), yellow fever (YFV), and Zika viruses (ZIKV). Currently, there are licensed human vaccines for DENV, JEV, TBEV and YFV, but not for WNV or ZIKV.
Guangyu Li, Cody Teleki, Tian Wang
openaire +3 more sources