Results 21 to 30 of about 68,853 (304)

Neuroinvasive flavivirus infections [PDF]

open access: yesReviews in Medical Virology, 2011
SUMMARYFlaviviruses, including Dengue, West Nile, Japanese encephalitis, and Tick‐borne encephalitis virus, are major emerging human pathogens, affecting millions of individuals worldwide. Many clinically important flaviviruses elicit CNS diseases in infected hosts, including traditional “hemorrhagic” viruses, such as Dengue. This review focuses on the
Gregorius J. Sips   +2 more
openaire   +3 more sources

Astrocytes in Flavivirus Infections [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
Virus infections of the central nervous system (CNS) can manifest in various forms of inflammation, including that of the brain (encephalitis) and spinal cord (myelitis), all of which may have long-lasting deleterious consequences. Although the knowledge of how different viruses affect neural cells is increasing, understanding of the mechanisms by ...
Maja Potokar   +2 more
openaire   +4 more sources

Molecular Determinants of Tissue Specificity of Flavivirus Nonstructural Protein 1 Interaction with Endothelial Cells

open access: yesbioRxiv, 2022
Flavivirus NS1 is secreted into the bloodstream from infected cells during a viral infection. Dengue virus NS1 contributes to severe dengue pathology such as endothelial dysfunction and vascular leak independently of the virus.
Nicholas T. N. Lo   +5 more
semanticscholar   +1 more source

Co-Circulation of Two Independent Clades and Persistence of CHIKV-ECSA Genotype during Epidemic Waves in Rio de Janeiro, Southeast Brazil

open access: yesPathogens, 2020
The Chikungunya virus infection in Brazil has raised several concerns due to the rapid dissemination of the virus and its association with several clinical complications.
Allison Araújo Fabri   +13 more
doaj   +1 more source

Molecular Insights into the Flavivirus Replication Complex

open access: yesViruses, 2021
Flaviviruses are vector-borne RNA viruses, many of which are clinically relevant human viral pathogens, such as dengue, Zika, Japanese encephalitis, West Nile and yellow fever viruses.
Kaïn van den Elsen, J. Quek, D. Luo
semanticscholar   +1 more source

Recombinant Envelope-Proteins with Mutations in the Conserved Fusion Loop Allow Specific Serological Diagnosis of Dengue-Infections [PDF]

open access: yes, 2015
Dengue virus (DENV) is a mosquito-borne flavivirus and a major international public health concern in many tropical and sub-tropical areas worldwide. DENV is divided into four major serotypes, and infection with one serotype leads to immunity against the
Barzon, Luisa   +5 more
core   +7 more sources

Flavivirus Concentrates Host ER in Main Replication Compartments to Facilitate Replication

open access: yesAdvanced Science, 2023
Flavivirus remodels the host endoplasmic reticulum (ER) to generate replication compartments (RCs) as the fundamental structures to accommodate viral replication.
Yali Ci   +6 more
doaj   +1 more source

Serological evidence for Japanese encephalitis and West Nile virus infections in domestic birds in Cambodia [PDF]

open access: yes, 2020
Mosquito-borne flaviviruses with an enzootic transmission cycle like Japanese encephalitis virus (JEV) and West Nile virus (WNV) are a major public health concern.
Auerswald, Heidi   +10 more
core   +2 more sources

Guapiaçu virus, a new insect-specific flavivirus isolated from two species of Aedes mosquitoes from Brazil

open access: yesScientific Reports, 2021
Classical insect-flaviviruses (cISFVs) and dual host-related insect-specific flavivirus (dISFV) are within the major group of insect-specific flavivirus.
Geovani de Oliveira Ribeiro   +23 more
doaj   +1 more source

Structure and function of capsid protein in flavivirus infection and its applications in the development of vaccines and therapeutics

open access: yesVeterinary Research, 2021
Flaviviruses are enveloped single positive-stranded RNA viruses. The capsid (C), a structural protein of flavivirus, is dimeric and alpha-helical, with several special structural and functional features.
Xingcui Zhang   +5 more
semanticscholar   +1 more source

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