Results 21 to 30 of about 15,113 (160)

Guapiaçu virus, a new insect-specific flavivirus isolated from two species of Aedes mosquitoes from Brazil

open access: yesScientific Reports, 2021
Classical insect-flaviviruses (cISFVs) and dual host-related insect-specific flavivirus (dISFV) are within the major group of insect-specific flavivirus.
Geovani de Oliveira Ribeiro   +23 more
doaj   +1 more source

TMEM41B Is a Pan-flavivirus Host Factor

open access: yesCell, 2020
Flaviviruses pose a constant threat to human health. These RNA viruses are transmitted by the bite of infected mosquitoes and ticks and regularly cause outbreaks. To identify host factors required for flavivirus infection we performed full-genome loss of
Hans-Heinrich Hoffmann   +13 more
semanticscholar   +2 more sources

30 years of dengue fatal cases in Brazil: a laboratorial-based investigation of 1047 cases

open access: yesBMC Infectious Diseases, 2018
Background Dengue viruses (DENV) have emerged and reemerged in Brazil in the past 30 years causing explosive epidemics. The disease may range from clinically asymptomatic infections to severe and fatal outcomes.
Priscila Conrado Guerra Nunes   +14 more
doaj   +1 more source

αVβ3 Integrin Expression Is Essential for Replication of Mosquito and Tick-Borne Flaviviruses in Murine Fibroblast Cells

open access: yesViruses, 2021
The Flavivirus genus includes a number of important viruses that are pathogenic to humans and animals and are responsible for outbreaks across the globe.
Vinicius Pinho dos Reis   +4 more
doaj   +1 more source

Capsid protein structure in Zika virus reveals the flavivirus assembly process

open access: yesNature Communications, 2020
Structures of flavivirus (dengue virus and Zika virus) particles are known to near-atomic resolution and show detailed structure and arrangement of their surface proteins (E and prM in immature virus or M in mature virus). By contrast, the arrangement of
T. Y. Tan   +11 more
semanticscholar   +1 more source

Structure and function of capsid protein in flavivirus infection and its applications in the development of vaccines and therapeutics

open access: yesVeterinary Research, 2021
Flaviviruses are enveloped single positive-stranded RNA viruses. The capsid (C), a structural protein of flavivirus, is dimeric and alpha-helical, with several special structural and functional features.
Xingcui Zhang   +5 more
semanticscholar   +1 more source

Compartmentalized replication organelle of flavivirus at the ER and the factors involved

open access: yesCellular and Molecular Life Sciences, 2021
Flaviviruses are positive-sense single-stranded RNA viruses that pose a considerable threat to human health. Flaviviruses replicate in compartmentalized replication organelles derived from the host endoplasmic reticulum (ER).
Y. Ci, Lei Shi
semanticscholar   +1 more source

Resveratrol as an epigenetic therapy for flavivirus infection: A narrative review

open access: yesAsian Pacific Journal of Tropical Medicine, 2023
Flaviviruses are a group of positive-stranded RNA viruses that cause a broad spectrum of severe illnesses in humans worldwide. Clinical manifestations of flavivirus infections range from mild febrile illness to hemorrhage, shock, and neurological ...
Kim-Ling Chin   +3 more
doaj   +1 more source

Culex flavivirus infection in a Culex pipiens mosquito colony and its effects on vector competence for Rift Valley fever phlebovirus

open access: yesParasites & Vectors, 2018
Background Rift Valley fever is a mosquito-borne zoonotic disease that affects domestic ruminants and humans. Culex flavivirus is an insect-specific flavivirus that naturally exists in field mosquito populations. The influence of Culex flavivirus on Rift
Sandra Talavera   +5 more
doaj   +1 more source

A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses

open access: yesNature Communications, 2021
The epidemic emergence of relatively rare and geographically isolated flaviviruses adds to the ongoing disease burden of viruses such as dengue. Structural analysis is key to understand and combat these pathogens.
J. Hardy   +10 more
semanticscholar   +1 more source

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