Characterizing the flavodoxin landscape in Clostridioides difficile [PDF]
Microbiology SpectrumClostridioides difficile infections have become a major challenge in medical facilities. The bacterium is capable of spore formation allowing the survival of antibiotic treatment. Therefore, research on the physiology of C. difficile is important for the
Daniel Troitzsch +8 more
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The long-chain flavodoxin FldX1 improves the biodegradation of 4-hydroxyphenylacetate and 3-hydroxyphenylacetate and counteracts the oxidative stress associated to aromatic catabolism in Paraburkholderia xenovorans [PDF]
Biological ResearchBackground Bacterial aromatic degradation may cause oxidative stress. The long-chain flavodoxin FldX1 of Paraburkholderia xenovorans LB400 counteracts reactive oxygen species (ROS). The aim of this study was to evaluate the protective role of FldX1 in P.
Laura Rodríguez-Castro +6 more
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Evolutionary Relationships Between Low Potential Ferredoxin and Flavodoxin Electron Carriers [PDF]
Frontiers in Energy Research, 2019 Proteins from the ferredoxin (Fd) and flavodoxin (Fld) families function as low potential electrical transfer hubs in cells, at times mediating electron transfer between overlapping sets of oxidoreductases.
Ian J. Campbell +5 more
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Assessing the Performance of Non-Equilibrium Thermodynamic Integration in Flavodoxin Redox Potential Estimation [PDF]
Molecules, 2023 Flavodoxins are enzymes that contain the redox-active flavin mononucleotide (FMN) cofactor and play a crucial role in numerous biological processes, including energy conversion and electron transfer.
Giuseppe Silvestri +6 more
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Frontiers in Plant Science, 2019 Tomato is the most important horticultural crop worldwide. Domestication has led to the selection of highly fruited genotypes, and the harvest index (HI), defined as the ratio of fruit yield over total plant biomass, is usually employed as a biomarker of
Martín L. Mayta +6 more
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Antimicrobial combinations against Helicobacter pylori including benzoxadiazol-based flavodoxin inhibitors: in vitro characterization [PDF]
Microbiology Spectrum, 2023 Antimicrobial resistance of Helicobacter pylori (Hp) threatens currently available treatment regimens and prompts the development of antimicrobial drugs against new bacterial targets.
Lilha Beyria +8 more
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Flavodoxin-Like Proteins Protect Candida albicans from Oxidative Stress and Promote Virulence. [PDF]
PLoS Pathogens, 2015 The fungal pathogen Candida albicans causes lethal systemic infections in humans. To better define how pathogens resist oxidative attack by the immune system, we examined a family of four Flavodoxin-Like Proteins (FLPs) in C. albicans.
Lifang Li +3 more
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Biomolecules, 2022 Flavodoxins are small electron transport proteins that are involved in a myriad of photosynthetic and non-photosynthetic metabolic pathways in Bacteria (including cyanobacteria), Archaea and some algae.
David C. Lamb +7 more
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Divergent functions of two clades of flavodoxin in diatoms mitigate oxidative stress and iron limitation [PDF]
eLife, 2023 Phytoplankton rely on diverse mechanisms to adapt to the decreased iron bioavailability and oxidative stress-inducing conditions of today’s oxygenated oceans, including replacement of the iron-requiring ferredoxin electron shuttle protein with a less ...
Shiri Graff van Creveld +5 more
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Antioxidants, 2022 Distinct isoforms of FAD-containing ferredoxin-NADP+ oxidoreductase (FNR) and ferredoxin (Fd) are involved in photosynthetic and non-photosynthetic electron transfer systems.
Takashi Iyanagi
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