Protein Science, 2018 Flavodoxins (Flds) are small proteins that shuttle electrons in a range of reactions in microorganisms. Flds contain a redox‐active cofactor, a flavin mononucleotide (FMN), and it is well established that when Flds are reduced by one electron, a peptide ...
I. Gudim +3 more
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HeliyonObjectives: The rise of antibiotic-resistant Streptococcus pneumoniae (Sp) poses a significant global health threat, urging the quest for novel antimicrobial solutions.
Juan José Galano-Frutos +7 more
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Crystal structure of AdoMet radical enzyme 7‐carboxy‐7‐deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe–4S] cluster engender flavodoxin specificity [PDF]
Protein Science, 2018 7‐Carboxy‐7‐deazaguanine synthase, QueE, catalyzes the radical mediated ring contraction of 6‐carboxy‐5,6,7,8‐tetrahydropterin, forming the characteristic pyrrolopyrimidine core of all 7‐deazaguanine natural products. QueE is a member of the S‐adenosyl‐L‐
T. Grell +6 more
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The Long and Short Flavodoxins [PDF]
Journal of Biological Chemistry, 2004 Jon López-Llano +8 more
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Exceptional Heme Tolerance in Serratia plymuthica: Proteomic Insights into Oxidative Stress Adaptation in the Aedes aegypti Midgut [PDF]
LifeSerratia plymuthica, isolated from the midgut of Aedes aegypti, displays remarkable resilience to hemin, a toxic hemoglobin byproduct generated during blood digestion.
Sâmella da Hora Machado +8 more
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Substitution of CH<sub>3</sub> by CH<sub>2</sub>F in 2-Methylerythritol Cyclodiphosphate Triggers Potent Inhibition of IspG with Concomitant Fluoride Ion Expulsion. [PDF]
ChemistryThe fluoromethyl analogue of MEcPP was identified as a very potent inhibitor of the oxygen‐sensitive [4Fe‐4S] metalloenzyme IspG. In the course of the IspG‐catalyzed transformation, this novel compound undergoes fluoride elimination, offering additional evidence for the involvement of a carbanionic intermediate in the mechanism of this enzyme ...
Witjaksono C +7 more
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Investigation of complex formation of flavodoxin and photosystem 1 by means of direct multiparticle computer simulation [PDF]
Компьютерные исследования и моделирование, 2009 Kinetics of complex formation between components of the photosynthetic electron transport chain - flavodoxin and membrane complex photosystem I has been studied using computer model based on methods of multiparticle simulation and Brownian dynamics.
A. M. Abaturova +3 more
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Suppression of Reactive Oxygen Species Accumulation in Chloroplasts Prevents Leaf Damage but Not Growth Arrest in Salt-Stressed Tobacco Plants. [PDF]
PLoS ONE, 2016 Crop yield reduction due to salinity is a growing agronomical concern in many regions. Increased production of reactive oxygen species (ROS) in plant cells accompanies many abiotic stresses including salinity, acting as toxic and signaling molecules ...
Anabella F Lodeyro +6 more
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bioRxiv, 2022 Phytoplankton rely on diverse mechanisms to adapt to the decreased iron bioavailability and oxidative stress-inducing conditions of today’s oxygenated oceans, including replacement of the iron-requiring ferredoxin electron shuttle protein with a less ...
Shiri Graff van Creveld +5 more
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The Candida albicans ζ-crystallin homolog Zta1 promotes resistance to oxidative stress
mSphere, 2023 The fungal pathogen Candida albicans is capable of causing lethal infections in humans. Its pathogenic potential is due in part to the ability to resist various stress conditions in the host, including oxidative stress.
Rafael M. Gandra +3 more
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