Results 241 to 250 of about 187,609 (313)

Flavonoids as Modulators of Neuroinflammation in Affective Disorders: A Narrative Review. [PDF]

Int J Mol Sci
Rosas-Sánchez GU, Rodríguez-Yoval R, German-Ponciano LJ, Gutiérrez-Coronado O, Gutiérrez PTV, Fernández-Demeneghi R, Martínez-Moreno AG, Muñoz-Carrillo JL, Soria-Fregozo C.   +8 more
europepmc   +1 more source

Post‐Translational Modifications of Key Proteins in Hematologic Malignancies: Carcinogenic Mechanisms, Biomarker Potential, and New Therapeutic Strategies

iLABMED, EarlyView.
This article reviews the pivotal role of post‐translational modifications of proteins in the development and progression of hematologic malignancies, and explores their clinical translation potential as novel biomarkers and therapeutic targets. ABSTRACT Post‐translational modifications (PTMs) of proteins have emerged as critical regulators in the ...
Yuxuan Han, Chaowei Zhang, Weiyi Yao, Qing Hong, Xinyu Tang, Yanan Zhu, Na Chen   +6 more
wiley   +1 more source

Enzymatic Modification of Flavonoids: Implications for Bioavailability, Bioactivity, and Therapeutic Potential Based on a Systematic Review and Bioinformatics Analysis. [PDF]

Antioxidants (Basel)
Cunha MCD, Cunha MCD, Ferrari YBS, de Melo NC, Carvalho LM, Ortega MM, Carvalho PO.   +6 more
europepmc   +1 more source

Functionally complementary bacterial inoculant coordinates arbuscular mycorrhizal fungi to improve Angelica sinensis root yield and quality

iMetaOmics, EarlyView.
Comprehensive understanding of how diverse PGPR strains enhance the rhizosphere microenvironment remains a considerable challenge. Here, we provide experimental evidence that a functionally synergistic composite microbial formulation can markedly enhance growth performance and improve the quality attributes in Angelica sinensis.
Zongyu Zhang, Yun Wang, Jiecai Zhao, Gaofeng Chen, Andéole Niyongabo Turatsinze, Liang Yue, Yuan Tian, Xiaofan Xie, Ailing Ye, Meilan Zhang, Lingling Wu, Zengxiang Guo, Yubao Zhang, Ruoyu Wang   +13 more
wiley   +1 more source

Environmental control of anthraquinone-flavonoid accumulation in wild plant species: biosynthetic pathways, ecological drivers, and adaptive significance. [PDF]

Front Plant Sci
Samarina LS, Terletskaya NV, Mussayeva AS.   +2 more
europepmc   +1 more source

Progress of metabolomics‐centric multi‐omics research in medicine

iMetaOmics, EarlyView.
The graphical abstract illustrates a holistic roadmap for metabolomics‐centric multi‐omics integration in medical research. The upper panel depicts the technological transition from traditional bulk analysis to high‐resolution single‐cell and spatial methodologies, specifically addressing inherent challenges such as molecular complexity and dynamic ...
Ziyi Wang, Shiwen Deng, Xiaoxu Wang, Xiao Chang, Na Guo, Peng Chen, Hongjun Yang   +6 more
wiley   +1 more source

Deciphering differentially expressed genes and a flavonoid analysis reveal that the metabolic flux shift of flavonoids lightens flower coloration in γ-irradiation-induced Dendrobium hybrid mutants. [PDF]

BMC Plant Biol
Kim J, Lee SH, Ryu J, Kim JH, Kim DG, Kim WJ, Ha TH, Kim SH.   +7 more
europepmc   +1 more source

Beyond “you are what you eat”: Unlocking gut microbiota‐mediated biotransformation of dietary phytochemicals

iMetaOmics, EarlyView.
The “efficacy paradox” of phytochemicals, low bioavailability yet significant health benefits, is associated with gut microbiota, which biotransforms dietary precursors into bioactive metabolites, enabling systemic effects. Thus, health outcomes of diet depend not just on intake “the rainbow”, but on gut microbial metabolism, redefining “you are what ...
Peng Yang, Ren‐You Gan
wiley   +1 more source

MaMYB12 and MaMYB308 antagonistically regulate flavonoid biosynthesis in mulberry (<i>Morus alba</i>): Implications for functional food ingredient development. [PDF]

Food Chem (Oxf)
Han S, Zhao T, Zhao J, Liu X, Xiao J, Huang H, Liu Z, Gai Y, Ji X.   +8 more
europepmc   +1 more source

Sexual dimorphism in hormone–gut microbiome associations across reproductive states in wild giant pandas

iMetaOmics, EarlyView.
Gut microbiota–host endocrine interactions in wild mammals remain poorly understood. Giant pandas experience seasonal dietary shifts and constrained annual reproduction, offering an ideal model to investigate microbiome–endocrine coupling. We integrated fecal hormone profiling, microsatellite‐based individual identification, and gut microbiome ...
Qinlong Dai, Xinyuan Cui, Chenyi Gao, Xiaoxiao Tang, Kaizhi Wen, Minhui Shi, Chen Zhang, Yue Liu, Xinru Yang, Qiuyu Huang, Lifeng Zhu   +10 more
wiley   +1 more source