Results 91 to 100 of about 11,677 (208)

Flavoprotein-mediated tellurite reduction: structural basis and applications to the synthesis of tellurium-containing nanostructures

Frontiers in Microbiology, 2016
The tellurium oxyanion tellurite (TeO32-) is extremely harmful for most organisms. It has been suggested that a potential bacterial tellurite resistance mechanism would consist of an enzymatic, NAD(P)H-dependent, reduction to the less toxic form ...
Mauricio Arenas-Salinas, Joaquín Ignacio Vargas, Wladimir Morales, Camilo Pinto, Pablo Muñoz, Fabian Alexis Cornejo, Benoit Pugin, Juan Sandoval, Waldo Diaz, Claudia Muñoz-Villagrán, Fernanda Jimena Rodríguez, Eduardo Morales, Claudio Christian Vásquez, Felipe Arenas   +13 more
doaj   +1 more source

Epilepsy Phenotype and EEG Finding of Rhythmic High‐Amplitude Delta With Superimposed Spikes (RHADS) in Succinate Dehydrogenase Deficiency

JIMD Reports, Volume 67, Issue 2, March 2026.
ABSTRACT Succinate dehydrogenase (SDH) serves a dual function as complex II of the electron transport chain and an enzyme of the tricarboxylic acid cycle. Pathogenic variants in subunits of SDH result in diverse clinical presentations, including typically autosomal recessive neurodegenerative disorders. Biallelic variants in the SDHA subunit most often
Aaron B. Bowen, Chiadika Nwanze, Cesar Alves, Lance Rodan, Anna Lecticia Pinto, Melissa A. Walker, Irina Anselm, Phillip L. Pearl   +7 more
wiley   +1 more source

Structural insights into the synthesis of FMN in prokaryotic organisms [PDF]

, 2017
Riboflavin kinases (RFKs) catalyse the phosphorylation of riboflavin to produce FMN. In most bacteria this activity is catalysed by the C-terminal module of a bifunctional enzyme, FAD synthetase (FADS), which also catalyses the transformation of FMN into
Herguedas, B., Hermoso, Juan A., Lans, I., Martínez-Júlvez, Marta, Medina, M., Sebastián, M.   +5 more
core   +1 more source

Immunostaining of P450c17, Aromatase and Oestrogen Receptor Alpha in Germ and Somatic Cells During Gonadal Development in Greater Rhea

Anatomia, Histologia, Embryologia, Volume 55, Issue 2, March 2026.
ABSTRACT The greater rhea (Rhea americana), the largest bird species in South America, has significant economic value due to its meat, eggs, leather, feathers and oil. However, its lack of external sexual dimorphism poses challenges for reproductive management and breeding programmes.
Marilú Cristofoli, Danielle Cristina Calado de Brito, Mayla Magalhães de Oliveira Alcobaça, Flavia Maria Pia Montenegro Donoso, Fabiana Morse Gosson Jorge, Marco Aurélio Schiavo Novaes, Moacir Franco Oliveira, Antônio Chaves de Assis Neto   +7 more
wiley   +1 more source

The investigation of interactions in the excited state of flavins using time-resolved spectroscopy [PDF]

In paper I the results obtained with a very short (3 nsec) intense laser pulse as excitation source are described. This pulse excites such a large amount of flavin molecules into higher excited singlet and triplet states that changes in absorption of ...
Visser, A.J.W.G.
core   +1 more source

The pyruvate and α-ketoglutarate dehydrogenase complexes of Pseudomonas aeruginosa catalyze pyocyanin and phenazine-1-carboxylic acid reduction via the subunit dihydrolipoamide dehydrogenase [PDF]

, 2017
Phenazines are a class of redox-active molecules produced by diverse bacteria and archaea. Many of the biological functions of phenazines, such as mediating signaling, iron acquisition, and redox homeostasis, derive from their redox activity.
Glasser, Nathaniel R., Hoy, Julie A., Newman, Dianne K., Wang, Benjamin X.   +3 more
core   +1 more source

Chemical Profiling, In Silico and In Vitro Studies to Identify Potential CDK2 and mTOR Inhibitor From Selaginella inaequalifolia (Hook. & Grev.) Spring Ethanolic Extracts

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
ABSTRACT The current study is aimed to reveal the phytoprofile of Selaginella inaequalifolia (Hook. & Grev.) Spring using GC–MS and predict the drug properties, toxicity, biological properties of S. inaequalifolia ethanolic extracts (SiEE) using in silico methods and in vitro toxicity assays, namely, MTT and BSLB assay.
Johnson Marimuthu Alias Antonysamy, Sivaraman Arumugam, Robin Charles Antony Arulraj, Anne Wincy Jacob Thomas, Henrique D. M. Coutinho   +4 more
wiley   +1 more source

Stress Conditioned Early‐Stage Screening in Biocatalysis

ChemCatChem, Volume 18, Issue 3, 12 February 2026.
Standard enzyme screening often overlooks industrial stress. We propose integrating conditions like pH shifts, low oxygen, interfacial deactivation, and high substrate/product levels into early high‐throughput assays. By measuring stress‐relevant metrics such as turnover under stress, cofactor efficiency, and solvent stability, the enzyme selection ...
Laia Vila‐Vidal, John M. Woodley, Elif Erdem   +2 more
wiley   +1 more source

Characterization of succinate dehydrogenase flavoprotein from Staphylococcus aureus ATCC 12600 [PDF]

Journal of Clinical and Scientific Research, 2013
Background: Staphylococcus aureus possesses complete tricarboxylic acid (TCA) cycle. Succinate dehydrogenase (SDH) links TCA cycle with electron transport chain and could therefore be an ideal target in the development of new antimicrobials.
V. Swarupa, S. Yeswanth, U.V. Prasad, D. Vasu, K. Venkatesh, L. Srikanth, P. Anitha, C. Manasa, P.Santhosh Kumar, G. Sowjenya, Y. Nandakumar, Abhijit Chaudhary, P.V.G.K. Sarma   +12 more
doaj  

Cryptochrome Interacts With Actin and Enhances Eye-Mediated Light Sensitivity of the Circadian Clock in Drosophila melanogaster

Frontiers in Molecular Neuroscience, 2018
Cryptochromes (CRYs) are a class of flavoproteins that sense blue light. In animals, CRYs are expressed in the eyes and in the clock neurons that control sleep/wake cycles and are implied in the generation and/or entrainment of circadian rhythmicity ...
Matthias Schlichting, Matthias Schlichting, Dirk Rieger, Paola Cusumano, Rudi Grebler, Rodolfo Costa, Gabriella M. Mazzotta, Charlotte Helfrich-Förster   +7 more
doaj   +1 more source